Identification | Back Directory | [Name]
L-Lysine homopolymer hydrobromide | [CAS]
25988-63-0 | [Synonyms]
PDL HBr POLY(LYS).HBR PDL Solution POLY-L-LYSINE Poly-L-lysine HBr Poly-L-lysine HCl L-Lysine homopolymer Polylysine hydrobromide POLY-L-LYSINE 70 000 HBR L-LYS-(L-LYS)N-L-LYS XHBR POLY-L-LYSINE HYDROBROMIDE Poly-L-lysine solution ( 0.1%) L-Lysine, homopolymer, hydrobromide POLY-L-LYSINE HYDROBROMIDE >300'000 POLY-L-LYSINE HYDROBROMIDE MOL WT 10 POLY-L-LYSINE HYDROBROMIDE MOL WT*15 POLY-L-LYSINE HYDROBROMIDE MOL WT*30 POLY-L-LYSINE HYDROBROMIDE MOL WT*40 POLY-L-LYSINE HYDROBROMIDE MOL WT*GR POLY-L-LYSINE HYDROBROMIDE, MOL WT 7 POLY-L-LYSIN-HYDROBROMIDE 30'000-70'000 Poly-L-lysine hydrobromide 4'000-15'000 POLY-L-LYSINE HYDROBROMIDE 5'000-10'000 POLY-L-LYSINE HYDROBROMIDE 10'000-20'000 POLY-L-LYSINE HYDROBROMIDE 20'000-30'000 POLY-L-LYSINE HYDROBROMIDE 30'000-70'000 POLY-L-LYSINE HYDROBROMIDE 70'000-150'000 POLY-L-LYSINE HYDROBROMIDE 150'000-300'000 POLY-L-LYSINE HYDROBROMIDE MOL WT 1000-5000 POLY-L-LYSINE HYDROBROMIDE MOL WT*4000-1 5000 Poly-L-Lysine Hydrobromide [MW 1, 500-8, 000] POLY-L-LYSINE HYDROBROMIDE MOL WT*30000- 70000 POLY-L-LYSINE HYDROBROMIDE MOL WT*15000- 30000 POLY-L-LYSINE HYDROBROMIDE, MOL. WT. 500-2,002 POLY-L-LYSINE HYDROBROMIDE, MOL. WT. 500-2,003 POLY-L-LYSINE HYDROBROMIDE MOL WT*150000 -300000 poly-L-lysine 0.01% solution mol. wt.*70,000-150, POLY-L-LYSINE HYDROBROMIDE MOL. WT.*70,0 00-150,000 POLY-L-LYSINE HYDROBROMIDE MOL WT*GREATE R THAN 3000 POLY-L-LYSINE HYDROBROMIDE MOL. WT.*>300 ,000 GAMMA- POLY-L-LYSINE 0.01% SOLUTION MOL. WT.*15 0,000-300,0 POLY-L-LYSINE HYDROBROMIDE MOL. WT.*30,0 00-70,000 G POLY-L-LYSINE 0.01% SOLUTION MOL. WT.*70 ,000-150,00 (2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]hexanoyl]amino]hexanoic acid (2S)-6-azanyl-2-[[(2S)-6-azanyl-2-[[(2S)-2,6-bis(azanyl)hexanoyl]amino]hexanoyl]amino]hexanoic acid | [EINECS(EC#)]
246-168-0 | [Molecular Formula]
(C6H12N2OHBr)n+H2O | [MDL Number]
MFCD00165424 | [MOL File]
25988-63-0.mol | [Molecular Weight]
146.19 |
Chemical Properties | Back Directory | [Appearance]
white powder | [storage temp. ]
2-8°C
| [form ]
lyophilized powder
| [color ]
White to off-white | [Stability:]
Stable. Incompatible with strong acids, strong bases. |
Hazard Information | Back Directory | [Chemical Properties]
white powder | [Definition]
ChEBI: The hydrobromide salt of poly(L-lysine). | [Uses]
- Poly-L-lysine coated glass coverslips have been used for mounting samples for scanning electron microscopy.
- Poly-L-lysine coated wells were used for trapping of PC-12 cells on electrodes.
- Poly-L-lysine-coated borosilicate glass slides were used for the seeding of viral vector-transduced cells.
| [Uses]
Poly-L-lysine polymers can be used in promoting cell adhesion to solid substrates, conjugation to methotrexate for increased drug transport, microencapsulation of islets, cell microencapsulation technology, microarray glass slide coating, and chromosomal preparations. It has also been used as a transfection agent for efficient labeling and to facilitate endocytosis. Lower molecular weight poly-L-lysine (30,000-70,000) is less viscuous in solution, but higher molecular weight versions provide more attachment sites per molecule. | [Uses]
Recommended as a cell culture substratum when using 0.5 ml of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application. | [General Description]
Poly-L-lysine hydrobromide is a nonspecific attachment factor in promoting cell adhesion to the substratum. | [Biochem/physiol Actions]
Poly-L-lysine is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When it is absorbed to the cell culture surface, poly-L-lysine functions to increase the number of positively charged sites available for cell binding. With cells that can digest poly-L-lysine, poly-D-lysine should be used as the attachment factor. |
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