| Identification | Back Directory | [Name]
4-Nitroindanone | [CAS]
24623-25-4 | [Synonyms]
4-Nitroindanone
Einecs 246-367-2
4-Nitroindan-1-one
4-Nitro-1-Indanone
2,3-Dihydro-4-nitroinden-1-one
4-nitro-2,3-dihydroinden-1-one
4-nitro-2,3-dihydro-1H-inden-1-one
1H-Inden-1-one, 2,3-dihydro-4-nitro-
2-(2,5-dimethylphenoxy)-1-cyclohexanone | [EINECS(EC#)]
246-367-2 | [Molecular Formula]
C9H7NO3 | [MDL Number]
MFCD06656901 | [MOL File]
24623-25-4.mol | [Molecular Weight]
177.16 |
| Chemical Properties | Back Directory | [Melting point ]
104-105 °C | [Boiling point ]
332.9±31.0 °C(Predicted) | [density ]
1.396±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [InChI]
InChI=1S/C9H7NO3/c11-9-5-4-6-7(9)2-1-3-8(6)10(12)13/h1-3H,4-5H2 | [InChIKey]
QIIWEVWPOBNGLP-UHFFFAOYSA-N | [SMILES]
C1(=O)C2=C(C([N+]([O-])=O)=CC=C2)CC1 |
| Hazard Information | Back Directory | [Description]
4-Nitroindanone (4-Nitro-1-indanone) is an important chemical reagent used as a raw material in organic synthesis for the preparation of other cyclic compounds. In biology, it can inhibit the cysteine protease thioredoxin reductase and also interacts with cardiac potassium channels and is cytotoxic to human erythrocytes. In a rat model of atrial fibrillation, 4-nitro-1-indanone was found to have antiarrhythmic properties. | [Uses]
4-Nitroindanone is a versatile building block, capable of undergoing microwave-assisted oxidation to form ninhydrins. 4-Nitroindanone also has pharmaceutical relevance, as its thiosemicarbazone derivative has anti-Trypanosoma cruzi properties. |
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