| Identification | More | [Name]
5-Methoxyindole-3-acetonitrile | [CAS]
2436-17-1 | [Synonyms]
(5-METHOXY-1H-INDOL-3-YL)ACETONITRILE
5-METHOXY-3-INDOLYLACETONITRILE
5-METHOXYINDOLE-3-ACETONITRILE
2-(5-Methoxy-1H-indol-3-yl)acetonitrile
5-METHOXY-3-INDOLYLACETONITRILE 97% | [Molecular Formula]
C11H10N2O | [MDL Number]
MFCD02094163 | [Molecular Weight]
186.21 | [MOL File]
2436-17-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Brown powder | [Melting point ]
65-69 °C (lit.) | [Boiling point ]
175-177 °C(Press: 0.01 Torr) | [density ]
1.224±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
16.02±0.30(Predicted) | [color ]
Very Dark Brown | [InChI]
InChI=1S/C11H10N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4H2,1H3 | [InChIKey]
ZBQCXEREMRGOCO-UHFFFAOYSA-N | [SMILES]
N1C2=C(C=C(OC)C=C2)C(CC#N)=C1 | [CAS DataBase Reference]
2436-17-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Brown powder | [Uses]
Reactant for preparation of (-)- and (+)-debromoflustramine B and its analogues as selective butyrylcholinesterase inhibitors
Reactant for preparation of carboline analogs as potent MAPKAP-K2 inhibitors
Reactant for preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment
Reactant for preparation of debromoflustramine B and labeled Me(3a)-13C-physostigmine
Reactant for preparation of physostigmine and physovenine
Reactant for preparation of phenethyl substituted indole derivatives as melatoninergic agonists and antagonists | [Uses]
5-Methoxyindole-3-acetonitrile is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors. |
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