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ChemicalBook--->CAS DataBase List--->2345-38-2

2345-38-2

2345-38-2 Structure

2345-38-2 Structure
IdentificationMore
[Name]

(TRIMETHYLSILYL)ACETIC ACID
[CAS]

2345-38-2
[Synonyms]

2-(TRIMETHYLSILYL)ACETIC ACID
(TRIMETHYLSILYL)ACETIC ACID
(trimethylsilyl)-aceticaci
(Trimethylsilyl)acetic acid, 98+%
[EINECS(EC#)]

219-067-4
[Molecular Formula]

C5H12O2Si
[MDL Number]

MFCD00042651
[Molecular Weight]

132.23
[MOL File]

2345-38-2.mol
Chemical PropertiesBack Directory
[Melting point ]

39-42 °C(lit.)
[Boiling point ]

90-95°C 10mm
[density ]

0.8830 (estimate)
[Fp ]

203 °F
[storage temp. ]

2-8°C
[solubility ]

Sol ethereal solvents.
[form ]

solid
[pka]

5.23±0.10(Predicted)
[Hydrolytic Sensitivity]

4: no reaction with water under neutral conditions
[Sensitive ]

Moisture Sensitive
[BRN ]

1679394
[CAS DataBase Reference]

2345-38-2(CAS DataBase Reference)
[NIST Chemistry Reference]

Acetic acid, (trimethylsilyl)-(2345-38-2)
[EPA Substance Registry System]

2345-38-2(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[RIDADR ]

UN3261
[WGK Germany ]

2
[RTECS ]

AK0843500
[F ]

3-10-21
[TSCA ]

No
[HazardClass ]

8
[PackingGroup ]

III
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Hydrochloric acid-->Diethyl ether-->Dichloromethane-->Sodium sulfate-->Sodium bicarbonate-->n-Butyllithium-->Aluminum chloride-->N-Bromosuccinimide-->Pentane-->Tetramethylsilane
Hazard InformationBack Directory
[Physical properties]

mp 40 °C.
[Uses]

(Trimethylsilyl)acetic acid may be used in chemical synthesis.
[Uses]

Trimethylsilylacetic Acid is a valuable reagent used in preparation of α,β-unsaturated carboxylic acids and α-trimethylsilylbutyrolactones,
[Preparation]

Obtained from the reaction of trimethylsilylmethylmagnesium chloride with carbon dioxide;3 can also be prepared by reaction of acetic acid with 2 equiv of lithium diisopropylamide, followed by chlorotrimethylsilane and hydrolysis.
Spectrum DetailBack Directory
[Spectrum Detail]

(TRIMETHYLSILYL)ACETIC ACID(2345-38-2)MS
(TRIMETHYLSILYL)ACETIC ACID(2345-38-2)1HNMR
(TRIMETHYLSILYL)ACETIC ACID(2345-38-2)13CNMR
(TRIMETHYLSILYL)ACETIC ACID(2345-38-2)IR1
(TRIMETHYLSILYL)ACETIC ACID(2345-38-2)IR2
(TRIMETHYLSILYL)ACETIC ACID(2345-38-2)Raman
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

(Trimethylsilyl)acetic acid, 98+%(2345-38-2)
[Sigma Aldrich]

2345-38-2(sigmaaldrich)
[TCI AMERICA]

Trimethylsilylacetic Acid,>97.0%(T)(2345-38-2)
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