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ChemicalBook--->CAS DataBase List--->22990-77-8

22990-77-8

22990-77-8 Structure

22990-77-8 Structure
IdentificationMore
[Name]

2-PIPERIDYLMETHYLAMINE
[CAS]

22990-77-8
[Synonyms]

2-(AMINOMETHYL)-1-PIPERIDINE
2-AMINOMETHYL PIPERIDINE
2AMPPR
2-PIPERIDINEMETHANAMINE
2-PIPERIDYLMETHYLAMINE
piperidine-2-methylamine
C-PIPERIDIN-2-YL-METHYLAMINE
2-(Aminomethyl)
1-(Piperidin-2-yl)methylamine
1-piperidin-2-ylmethanamine
2-AMINOMETHYL PIPERIDINE 99%
Piperidine-2-methanamine
[EINECS(EC#)]

245-371-1
[Molecular Formula]

C6H14N2
[MDL Number]

MFCD03428050
[Molecular Weight]

114.19
[MOL File]

22990-77-8.mol
Chemical PropertiesBack Directory
[Boiling point ]

63-66°C/12mm
[density ]

0.9406 g/mL at 25 °C
[refractive index ]

1.4850
[Fp ]

63-66°C/12mm
[storage temp. ]

-20°C
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
[form ]

neat
[pka]

10.32±0.29(Predicted)
[color ]

Clear Colorless
[BRN ]

102994
[InChIKey]

RHPBLLCTOLJFPH-UHFFFAOYSA-N
[CAS DataBase Reference]

22990-77-8(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

R34:Causes burns.
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

2735
[WGK Germany ]

2
[HazardClass ]

8
[PackingGroup ]

III
[HS Code ]

29333990
Raw materials And Preparation ProductsBack Directory
[Raw materials]

2-Picolylamine-->Diethyl ether-->Water-->Hydrochloric acid-->2-Cyanopyridine
[Preparation Products]

Flecainide
Hazard InformationBack Directory
[Uses]

Reactant for reversible aminal formation

Reactant for synthesis of:
  • Annulated N-heterocyclic carbene ligands
  • M3 Muscarinic receptor antagonists
  • Selective 5-ht5A receptor antagonists
  • Ternary platinum(II) complexes
[Uses]

2-Piperidinemethanamine is used in the synthesis of compounds exhibiting anti-osteoclast and anti-osteoblast activity. It also is used in the synthesis of potent antibacterial.
[Purification Methods]

Dry (over Na2SO4) and distil the piperidine under vacuum from KOH. It has been purified via the Reinekate salt (m 173-174o) and its dipicrate salt (m 201o, from H2O). [Norton et al. J Am Chem Soc 68 1330 1946, Mortimer Aust J Chem 11 84 1958, Augustine J Am Chem Soc 81 4667 1959, Beilstein 22 III/IV 3765.]
Well-known Reagent Company Product InformationBack Directory
[Alfa Aesar]

2-(Aminomethyl)piperidine, 98%(22990-77-8)
[Sigma Aldrich]

22990-77-8(sigmaaldrich)
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