| Identification | More | [Name]
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone | [CAS]
22246-18-0 | [Synonyms]
(1H)-7-HYDROXY-3,4-DIHYDRO-2-QUINOLINONE
3,4-DIHYDRO-7-HYDROXYCARBOSTYRIL
7-HYDROXY-1,2,3,4-TETRAHYDRO-2-QUINOLINONE
7-HYDROXY-1,2,3,4-TETRAHYDROQUINOLIN-2-ONE
7-HYDROXY-1,2,3,4-TETRAHYDROQUINOLINE-2-ONE
7-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE
7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE
7-HYDROXY-3,4-DIHYDRO-2-OXO-(1H)-QUINOLINE
7-HYDROXY-3,4-DIHYDROCARBOSTYRIL
7-HYDROXY-3,4-DIHYDRO CARBOSTYRYL
7-HYDROXY-3,4-DIHYDROQUINOLIN-2(1H)-ONE
7-HYDROXY-3,4-DIHYDRO-QUINOLIN-2-ONE
8-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE
AURORA KA-4813
7-Hydroxy-2(1H)-3,4-dihydroquinolinone
7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE3,4-DIHYDRO-7-HYDROXY-2-(1H)-QUINOLINONE
3,4-Dihydro-7-Hydroxy-2(1H)-Quinlinone
7-Hydroxy-2-Oxo-3,4-Dihydroquinoline
7-Hydroxy-3,4-dihydro-2(1H)-qu
3,4-DIHYDRO-7-HYDROXY-2(1H)-QUINOLINONE /7-HQ | [Molecular Formula]
C9H9NO2 | [MDL Number]
MFCD06410891 | [Molecular Weight]
163.17 | [MOL File]
22246-18-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Pale Yellow Powder | [Melting point ]
233-237 °C | [Boiling point ]
403.7±45.0 °C(Predicted) | [density ]
1.282±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
9.60±0.20(Predicted) | [color ]
Pale Yellow | [InChIKey]
LKLSFDWYIBUGNT-UHFFFAOYSA-N | [CAS DataBase Reference]
22246-18-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R43:May cause sensitization by skin contact. | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
3 | [HS Code ]
29334900 |
| Questions And Answer | Back Directory | [Description]
3,4-Dihydro-7-hydroxy-2 (1H)-quinolinone is a useful organic and pharmaceutical intermediate. It can be used as the precursor of aripiprazole1, which is an antipsychotic medication. It is also an antitumor agent and hydroxyindole analog inhibitor tyrosinase melanoma.
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| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Powder | [Uses]
3,4-Dihydro-7-hydroxyquinoline-2(1H)-one (Aripiprazole EP Impurity A) is an antitumor agent. Hydroxyindole analog inhibitor tyrosinase melanoma. This compound is also used in the preparation of aripiprazole (A771000). |
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