Identification | More | [Name]
2-(4-FLUOROBENZYLAMINO)ETHANOL | [CAS]
22116-33-2 | [Synonyms]
CHEMBRDG-BB 4004526 2-(4-FLUOROBENZYLAMINO)ETHANOL 2-(4-Fluorobenzyl)-Ethanolamino 2-(4-FLUOROBENZYLAMINO)ETHANOL,98% 2-[(4-fluorophenyl)methylamino]ethanol Ethanol-2-(4-(fluorophenyl)methyl)amine Ethanol, 2-[[(4-fluorophenyl)Methyl]aMino]- 2-[(4-fluorobenzyl)amino]ethanol(SALTDATA: FREE) | [Molecular Formula]
C9H12FNO | [MDL Number]
MFCD04560903 | [Molecular Weight]
169.2 | [MOL File]
22116-33-2.mol |
Questions And Answer | Back Directory | [Uses]
2-[(4-Fluorobenzyl)amino]ethanol is used in preparation of (Fluorobenzyl)aminomethylmorpholine salt and its application in preparation of mosapride citrate. |
Hazard Information | Back Directory | [Application]
2-(4-FLUOROBENZYLAMINO)ETHANOL can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
P-fluorobenzaldehyde (24.8 g, 0.2 mol) and 2-aminoethanol (15.3 g, 0.25 mol) were added to a reaction flask containing methanol (250 ml), heated to reflux, and kept at 65 ?? C for 4 h.The temperature was lowered, sodium borohydride (9.2 g 0.24 mol) was added, and the reaction was stirred, the reaction was completed, filtered, and concentrated.The fraction was collected to give 2-(4-fluorobenzylamino)ethanol as a colorless oily liquid (yield: 90.2%, purity 98.7%). |
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