Identification | More | [Name]
Potassium oxonate | [CAS]
2207-75-2 | [Synonyms]
4,6-DIHYDROXY-1,3,5-TRIAZINE-2-CARBOXYLIC ACID, POTASSIUM SALT ALLANTOXANIC ACID POTASSIUM SALT LABOTEST-BB LT00138090 OTERACIL POTASSIUM OXONIC ACID POTASSIUM SALT Potassium 1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylate POTASSIUM 4,6-DIHYDROXY-1,3,5-TRIAZINE-2-CARBOXYLATE POTASSIUM ALLANTOXANATE POTASSIUM OXONATE 1,4,5,6-tetrahydro-4,6-dioxo-s-triazine-2-carboxylicacid,potassiumsalt 5-azaoroticacid,potassiumsalt kox potassiumazaorotate oxonic acid potassium OXONIC ACID POTASSIUM SALT 97.5% Oxonic acid, potassium salt, 97.50% POTASSIUMOXONATE/OTERACILPOTASSIUM Oteracil potassium(OXO) 4,6-Dihydroxy-1,3,5-triazine-2-carboxylic acid potassium salt, Allantoxanic acid (OXO)Oteracil potassium | [EINECS(EC#)]
218-627-5 | [Molecular Formula]
C4H2KN3O4 | [MDL Number]
MFCD00010565 | [Molecular Weight]
195.17 | [MOL File]
2207-75-2.mol |
Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
300 °C(lit.)
| [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated) | [form ]
Powder | [color ]
White | [Water Solubility ]
Soluble in hot water. | [Usage]
Antitumor effect potentiator and antitumor agent | [Detection Methods]
T | [CAS DataBase Reference]
2207-75-2(CAS DataBase Reference) |
Safety Data | Back Directory | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
RR4580000
| [HS Code ]
29349990 |
Hazard Information | Back Directory | [Description]
Oxonic acid is a uricase inhibitor that prevents metabolism and excretion of uric acid (Item No. 16219) and induces embryotoxicity and nephrotoxicity in rats.1 It is a component of S-1, a mixture containing a prodrug of the antitumor agent 5-fluorouracil (5-FU; Item No. 14416), that suppresses the gastrointestinal toxicity of 5-FU without inhibiting its antitumor activity in rats.2 Formulations containing oxonic acid have been used to treat gastric, pancreatic, lung, head, neck, and breast carcinomas.3 | [Chemical Properties]
Off-White Solid | [Uses]
Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats. It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism. | [Uses]
Antitumor effect potentiator and antitumor agent | [Uses]
Oxonic acid potassium salt is an inhibitor of uricase. The product from Sigma has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism. | [Definition]
ChEBI: Potassium 2,6-dihydroxytriazinecarboxylate is an organic molecular entity. |
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