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ChemicalBook--->CAS DataBase List--->2174002-16-3

2174002-16-3

2174002-16-3 Structure

2174002-16-3 Structure
IdentificationBack Directory
[Name]

Palbociclib-025
[CAS]

2174002-16-3
[Synonyms]

Palbociclib E
N-Formyl Palbociclib
Palbociclib Impurity 025
1-Piperazinecarboxaldehyde, 4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-
4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde? (Palbociclib Impurity)
Palbociclib impurity 27/Palbociclib N-Formyl Impurity/4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carbaldehyde
[Molecular Formula]

C25H29N7O3
[MOL File]

2174002-16-3.mol
[Molecular Weight]

475.54
Chemical PropertiesBack Directory
[Boiling point ]

765.3±70.0 °C(Predicted)
[density ]

1.389±0.06 g/cm3(Predicted)
[solubility ]

Chloroform (Slightly), DMSO (Slightly)
[form ]

Solid
[pka]

5.24±0.10(Predicted)
[color ]

Light Yellow to Very Dark Yellow
Hazard InformationBack Directory
[Uses]

Palbociclib N-Aldehyde is an intermediate in synthesizing Palbociclib N-b-D-Glucuronide Sodium Salt (P139910), a derivative of Palbociclib (P139900) which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
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