| Identification | Back Directory | [Name]
Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- | [CAS]
571190-22-2 | [Synonyms]
Palbociclib-1
Palbociclib-010
6-Desacetyl Palbociclib
8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)a...
8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
8-Cyclopentyl-5-methyl-2-[[(5-piperazin-1-ylpyridin-2-yl)]amino]-8H-pyrido[2,3-d]pyrimidin-7-one
8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]- Pyrido[2,3-d]pyrimidin-7(8H)-one
Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-
Palbociclib impurity 12/8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one | [Molecular Formula]
C22H27N7O | [MOL File]
571190-22-2.mol | [Molecular Weight]
405.5 |
| Chemical Properties | Back Directory | [Melting point ]
>200oC (dec.) | [Boiling point ]
651.3±65.0 °C(Predicted) | [density ]
1.301±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C, Inert atmosphere | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly) | [form ]
Solid | [pka]
8.66±0.10(Predicted) | [color ]
Light Yellow |
| Hazard Information | Back Directory | [Uses]
6-Desacetyl Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. |
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