| Identification | More | [Name]
2-Amino-6-chlorobenzoic acid | [CAS]
2148-56-3 | [Synonyms]
2-AMINO-6-CHLOROBENZOIC ACID
6-AMINO-2-CHLOROBENZOIC ACID
6-CHLOROANTHRANILIC ACID
RARECHEM AL BO 1514
TIMTEC-BB SBB001735
Benzoic acid, 2-amino-6-chloro-
6-Chloro-2-aminobenzoic acid
2-choro-6-Aminobenzoic Acid
BENZOIC ACID, 2-AMINO-6-CHLORO-(9CI)
2-AMINO-6-CHLOROBENZOIC ACID(6-CHLOROANTHRANILIC ACID)
6-AMINO-2-CHLOROBENZOC ACID
6-Chloroanthranilic acid (COOH=1)
2-AMINO-6-CHLOROBENZOIC ACID 98% | [EINECS(EC#)]
218-416-8 | [Molecular Formula]
C7H6ClNO2 | [MDL Number]
MFCD00051530 | [Molecular Weight]
171.58 | [MOL File]
2148-56-3.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
158-160 °C (lit.) | [Boiling point ]
250°C (rough estimate) | [density ]
1.3246 (rough estimate) | [refractive index ]
1.5560 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
Crystalline Powder | [pka]
0.97±0.10(Predicted) | [color ]
Light yellow to beige | [Water Solubility ]
Very soluble in water. Soluble in methanol. | [BRN ]
2804041 | [InChIKey]
SZCPTRGBOVXVCA-UHFFFAOYSA-N | [CAS DataBase Reference]
2148-56-3(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Amino-6-chlorobenzoic acid(2148-56-3) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29224999 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
2-Amino-6-chlorobenzoic acid is used as intermediate for medicine. | [Application]
The tricyclohexyltin 2-amino-6-chlorobenzoate was synthesized by the reaction of the tricyclohexyltin hydroxide with the 2-amino-6-chlorobenzoic acid. | [Preparation]
A, in the reaction vessel being provided with agitator, thermometer, reflux condenser, Dropping funnel, add cerium chloride 0.16mol, 4-hydroxy 3-methoxybenzene ethanol solution 0.19mol, Klorvess Liquid 400-500ml, control mixing speed and exist 160-190rpm, rising solution temperature, to 60-65°C, is slowly added to 2-chloro-6-nitrobenzoyl acid solution 0.13mol, sulfurous acid Hydrogen potassium solution 200ml, raises mixing speed to 260-310rpm, back flow reaction 5-7h；
B, reduction solution temperature, to 15-19°C, separate out solid, filter, and add diammonium hydrogen citrate solution 150-in filtrate 180ml, concentrating under reduced pressure, separate out solid, filter, dehydrant is dehydrated, brine, and pyridine solution washs, ethyl acetate solution Middle recrystallization, obtains crystal 2-amino-6-chlorobenzoic acid (C7H6ClNO2). | [reaction suitability]
reaction type: solution phase peptide synthesis |
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