| Identification | More | [Name]
BOC-TRANS-4-FLUORO-L-PROLINE | [CAS]
203866-14-2 | [Synonyms]
(2S,4R)-4-FLUORO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
BOC-TRANS-4-FLUORO-L-PROLINE
N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID
N-BOC-TRANS-4-FLUORO-L-PROLINE
N-T-BOC-TRANS-4-FLUORO-L-PROLINE
N-(TERT-BUTOXYCARBONYL)-(2S,4R)-4-FLUOROPROLINE
(2R,4S)-N-Boc-trans-4-Fluoro-D-proline methyl ester
(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline
(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N4-BOC protected
trans-4-Fluoro-L-proline, N-BOC protected
(2S,4R)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid
(2R,4S)-N-BOC-4-FLUORO-D-PROLINE
(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N-BOC protected
(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid
(2S,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid
N-(tert-Butoxycarbonyl)-trans-4-fluoro-L-proline | [Molecular Formula]
C10H16FNO4 | [MDL Number]
MFCD06796085 | [Molecular Weight]
233.24 | [MOL File]
203866-14-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
115-119°C | [Boiling point ]
346.0±42.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [refractive index ]
-69 ° (C=1, MeOH) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [pka]
3.53±0.40(Predicted) | [color ]
White to Almost white | [optical activity]
[α]22/D -65.0±5°, c = 1 in chloroform | [InChIKey]
YGWZXQOYEBWUTH-RQJHMYQMSA-N | [CAS DataBase Reference]
203866-14-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves . | [WGK Germany ]
3 | [HazardClass ]
IRRITANT | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents. |
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