| Identification | More | [Name]
DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID | [CAS]
20263-07-4 | [Synonyms]
(+/-)-2-AMINO-4-PHOSPHONOBUTYRIC ACID
(+/-)-AP-4
AP-4
DL-2-AMINO-4-PHOSPHONOBUTANOIC ACID
DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID
DL-AP4
DL-2-AMINO-4-PHOSPHONOBUTYRIC ACID (DL-AP4)
DL-APB | [Molecular Formula]
C4H10NO5P | [MDL Number]
MFCD00013999 | [Molecular Weight]
183.1 | [MOL File]
20263-07-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3 |
| Hazard Information | Back Directory | [Uses]
(±)-2-Amino-4-phosphonobutyric acid may be used as a glutamic acid receptor blocker in perfusion solution in the eye tissue electroretinography studies. | [General Description]
(±)-2-Amino-4-phosphonobutyric acid or DL-AP4 is a group III nonselective metabotropic glutamate receptor (mGluR) agonist. L-2-amino-4-phosphonobutyric acid (L-Ap4) displays close to 500-fold selectivity for group III mGluRs. | [Biological Activity]
Broad spectrum EAA ligand. See separate isomers (D-(-)-2-Amino-4-phosphonobutyric acid and L-(+)-2-Amino-4-phosphonobutyric acid). |
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Sigma-Aldrich
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