| Identification | Back Directory | [Name]
H-TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG-OH | [CAS]
191936-91-1 | [Synonyms]
TAT (47-57)
YGRKKRRQRRR
HIV-1 Tat (47-57)
HIV-I TAT Protein Peptide
HIV-1 TAT PROTEIN (47-57)
HIV-1 TAT PROTEIN PEPTIDE
TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG
H-TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG-OH
TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG: YGRKKRRQRRR
H-TYR-GLY-ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-ARG-OH USP/EP/BP
L-Arginine, L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl- | [Molecular Formula]
C64H118N32O14 | [MDL Number]
MFCD07366706 | [MOL File]
191936-91-1.mol | [Molecular Weight]
1559.83 |
| Hazard Information | Back Directory | [General Description]
HIV-1 trans-activator of transcription (Tat) is an 11kDa protein, which regulates HIV-1 gene expression at the level of transcription and protein synthesis. It is located in the nucleus of infected cells. HIV-1 Tat functions as a transcriptional activator for the synthesis of full-length viral RNA. It induces RNA splicing. Tat is an RNA binding protein, which particularly recognizes trans activator response element (TAR) from the HIV-1 RNA molecule. | [Biochem/physiol Actions]
Synthetic peptide that includes the sequence responsible for the cellular uptake of the human immunodeficiency virus-1 Tat protein, consisting of the polycationic region 49–57. The peptide is part of the protein transduction domain (PTD) and was shown to enable the introduction of nucleic acids into cells. | [storage]
Store at -20°C |
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