Identification | More | [Name]
(R)-1-Boc-3-Aminopiperidine | [CAS]
188111-79-7 | [Synonyms]
1-PIPERIDINECARBOXYLIC ACID, 3-AMINO-, 1,1-DIMETHYLETHYL ESTER, (3R)- 1-T-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE 1-tert-butyloxycarbonyl-3-r-aminopiperidine (R)-1-BOC-3-AMINOPIPERIDINE (R)-1-BOC-3-AMINOPIPERIDINE HCL (R)-1-BOC-3-AMNIOPIPERIDINE (R)-1-BOC-3-PIPERIDINAMINE (R)-1-N-BOC-3-AMINO PIPERIDINE (R)-1-TERT-BUTYLOXYCARBONYL-3-AMINOPIPERIDINE HYDROCHLORIDE (R)-3-AMINO-1-BOC-PIPERIDINE (R)-3-AMINO-1-BOC-PIPERIDINE HYDROCHLORIDE (R)-3-AMINO-1-N-BOC-PIPERIDINE (R)-3-AMINO-N-BOC-PIPERIDINE (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HCL (R)-BOC-PIP(3-NH2) HCL (R)-N-BOC-3-AMINOPIPERIDINE (R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE TERT-BUTYL (R)-3-AMINO-1-PIPERIDINECARBOXYLATE (R)-3-Amino-1-N-Boc-Piperidine (R)-1-Boc-3-Aminopiperidine | [EINECS(EC#)]
628-472-9 | [Molecular Formula]
C10H20N2O2 | [MDL Number]
MFCD04973125 | [Molecular Weight]
200.28 | [MOL File]
188111-79-7.mol |
Chemical Properties | Back Directory | [alpha ]
28.5 º (c=1, DMF) | [Boiling point ]
277.3±33.0 °C(Predicted) | [density ]
1.041±0.06 g/cm3(Predicted) | [refractive index ]
1.4730 | [storage temp. ]
Store under inert gas | [solubility ]
Chloroform (Slightly), DMF (Slightly), DMSO (Slightly) | [form ]
Liquid | [pka]
10.35±0.20(Predicted) | [color ]
Colorless to pale yellow | [optical activity]
[α]/D -28.5±2°, c = 1 in DMF | [Water Solubility ]
Immiscible with water. | [Sensitive ]
Moisture Sensitive | [InChI]
InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1 | [InChIKey]
AKQXKEBCONUWCL-MRVPVSSYSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1 | [CAS DataBase Reference]
188111-79-7(CAS DataBase Reference) |
Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN2735 | [WGK Germany ]
3
| [F ]
10-34 | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29333990 |
Hazard Information | Back Directory | [Chemical Properties]
Yellow liquid | [Uses]
(R)-(-)-3-Amino-1-Boc-piperidine is used as an intermediate in the manufacture of various substances such as pharmaceuticals. | [General Description]
(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents. |
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