Identification | Back Directory | [Name]
PREGNENOLONE SULFATE SODIUM SALT | [CAS]
1852-38-6 | [Synonyms]
Pregnenolone 3-Sulfate PREGNENOLONE SULFATE SODIUM SodiuM Pregnenolone-d4 Sulfate 5-Pregnen-3β-ol-20-one sulfate Pregnenolone sulphate Na+ salt PREGNENOLONE SULFATE SODIUM SALT PREGNENOLONE SULPHATE, SODIUM SALT Pregnenolone-3-sulfate SodiuM Salt 3-Hydroxypregn-5-en-20-one sulfate Pregnenolone monosulfate sodium salt 3β-Hydroxy-5-pregnen-20-one 3-sulfate 5-pregnen-3B-ol-20-one sulfate sodium 5-PREGNEN-3BETA-OL-20-ONE3-SULFATE SODIUM 5-PREGNEN-3B-OL-20-ONE SULFATE SODIUM SALT 5-PREGNEN-3BETA-OL-20-ONE SULFATE SODIUM SALT 3-HYDROXYPREGN-5-EN-20-ONE SULFATE SODIUM SALT (3β)-3-(Sulfooxy)-pregn-5-en-20-one sodium salt 5-Pregnen-3-beta-ol-2o-one sulphate,sodium salt 5-PREGNEN-3-BETA-OL-20-ONE SULPHATE, SODIUM SALT 3B-HYDROXY-5-PREGNEN-20-ONE 3-SULFATE SODIUM SALT 3β-Hydroxy-5-pregnen-20-one monosulfate sodium salt 3-BETA-HYDROXY-5-PREGNEN-20-ONE 3-SULPHATE, SODIUM SALT PREGNENOLONE SULFATE SODIUM SALT 5-PREGN EN-3B-OL-20-ON 3β-Hydroxy-5-pregnen-20-one 3-sulfate, 3-Hydroxypregn-5-en-20-one sulfate, 5-Pregnen-3β-ol-20-one sulfate | [Molecular Formula]
C21H31NaO5S | [MDL Number]
MFCD00056177 | [MOL File]
1852-38-6.mol | [Molecular Weight]
418.52 |
Chemical Properties | Back Directory | [Melting point ]
192 °C(lit.)
| [storage temp. ]
Store at -20°C | [solubility ]
methanol and water: 1.93 mg/mL
| [form ]
A crystalline solid | [color ]
White to off-white |
Hazard Information | Back Directory | [Description]
Pregnenolone sulfate is a metabolite of the natural steroid hormone pregnenolone . Pregnenolone sulfate modulates NMDA receptor responses to exogenously applied glutamate and stimulates transient receptor potential melastatin 3 (TRPM3). | [Uses]
Pregnenolone sulfate sodium salt has been used as sigma-1 receptor (σ1R) agonist. It has also been used in the stimulation and as a ligand for transient receptor potential melastatin-3 (TRPM3). | [Uses]
Pregnenolone Sulfate Sodium Salt, is a metabolite of Pregnenolone (P712200). It is also a neuroactive steroid, a potent and efficacious modulators of the GABAA receptor. | [Biochem/physiol Actions]
Pregnenolone sulfate is a neurosteroid and a neuromodulator. It is involved in the stimulation of N-methyl-D-aspartate receptor (NMDA), γ-Aminobutyric acid type A (GABAA?) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA-kainate). It activates transient receptor potential melastatin (TRPM3) which is a calcium-permeable ion channel. It improves schizophrenia and behavioral anomalies by modulating NMDA mediated Ser/Thr kinase - glycogen synthase kinase 3 β (AKT/GSK3β) signaling pathway. | [storage]
Store at +4°C |
|
Company Name: |
Spectrum Chemical Manufacturing Corp.
|
Tel: |
021-021-021-67601398-809-809-809 15221380277 |
Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
Company Name: |
CHIRIAL CO.LTD
|
Tel: |
025-58218501 19941513806 |
Website: |
https://www.chirial.com |
Company Name: |
Energy Chemical
|
Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
|