| Identification | More | [Name]
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE | [CAS]
1837-57-6 | [Synonyms]
2-ETHOXY-6,9-DIAMINOACRIDINE LACTATE
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
ACRINOL
ETHACRIDINE LACTATE
ETHODIN
RIVANOL
2,5-diamino-7-ethoxyacridinelactate
2-aethoxy-6,9-diaminoacridinlactat
2-ethoxy-6,9-diaminoacridinelactatehydrate
2-ethoxy-6,9-diaminoacridiniumlactate
6,9-diamino-2-ethoxy-acridincompd.withlacticacid(1:1)
6,9-diamino-2-ethoxy-acridinmonolactate
6,9-diamino-2-oxyethylacridinelactate
9-acridinediamine,2-ethoxy-2-hydroxypropanoate(1:1)
acrolactine
flavitrol
lacticacid,compd.with6,9-diamino-2-ethoxyacridine(1:1)
metifex
propanoicacid,2-hydroxy-,compd.with7-ethoxy-3,9-acridinediamine(1:1)
rimaon | [EINECS(EC#)]
217-408-1 | [Molecular Formula]
C18H21N3O4 | [MDL Number]
MFCD00013149 | [Molecular Weight]
343.38 | [MOL File]
1837-57-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Pale-yellow crystals. Slowly soluble in 15 parts water; soluble
in 9 parts boiling water; soluble in 110 parts alcohol
(22C). Solutions are yellow, fluorescent, and stable
to boiling. | [Melting point ]
235°C | [Boiling point ]
478.66°C (rough estimate) | [density ]
1.2764 (rough estimate) | [refractive index ]
1.5855 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO:84.5(Max Conc. mg/mL);246.08(Max Conc. mM)
Water:69.0(Max Conc. mg/mL);104.84(Max Conc. mM) | [Uses]
Bactericide, surgical antisepsis, preparation of
pure γ-globulin. | [CAS DataBase Reference]
1837-57-6(CAS DataBase Reference) | [EPA Substance Registry System]
Rivanol (1837-57-6) |
| Safety Data | Back Directory | [Safety Profile]
Poison by
subcutaneous, intraperitoneal, and
intravenous routes. Experimental
reproductive effects. An antiseptic. When
heated to decomposition it emits toxic
fumes of NOx. |
| Hazard Information | Back Directory | [Chemical Properties]
Pale-yellow crystals. Slowly soluble in 15 parts water; soluble
in 9 parts boiling water; soluble in 110 parts alcohol
(22C). Solutions are yellow, fluorescent, and stable
to boiling. | [Originator]
Rivanol,Sopharma | [Definition]
ChEBI: Acrinol is an organic molecular entity. | [Manufacturing Process]
A mixture of 250 parts by volume of ethylene glycol, 50 parts by weight of 6-
nitro-9-chloro-2-ethoxyacridine (obtained by reaction of 52 parts by weight of
30 nitro-4-ethoxy-diphenylamine-6-carboxylic acid with phosphorous
oxychloride), 10 parts by weight of ammonium chloride, and 11 parts by
weight of urea were heated to 170°C and stirred for 1 hour at 170°-175°C.
Subsequently, the whole was cooled to 100°C, the reaction mixture was
introduced into 1000 parts by volume of water, rendered acidic to Congo
paper by means of hydrochloric acid and the 6-nitro-9-amino-2-ethoxyacridine
precipitated was filtered off. By reduction iron according to Bechamp, 6,9-
diamino-2-ethoxy-acridine hydrochloride was obtained with yield of 83% as
the yellow needles. The base was prepared by adding an equivalent of NaOH.
MP: 124°C.
In practice it is usually used as lactate. | [Therapeutic Function]
Antiseptic, Antibacterial |
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