| Identification | More | [Name]
Methyltriphenylphosphonium bromide | [CAS]
1779-49-3 | [Synonyms]
METHYLTRIPHENYLPHOSPHONIUM BROMIDE
TMP
TRIPHENYLMETHYLPHOSPHONIUM BROMIDE
Bromo(methyl)triphenylphosphorane
methyltriphenyl-phosphoniubromide
Phosphonium, methyltriphenyl-, bromide
Phosphonium,methyltriphenyl-,bromide
MethyltriphenylphosphoniumBromide>98%
METHYL TRIPHENYL PHOSPHONIUM BROMIDE LOW WATER
Methyltriphenylphosphanium bromide
Methy triphenylphosphonium | [EINECS(EC#)]
217-218-9 | [Molecular Formula]
C19H18BrP | [MDL Number]
MFCD00011804 | [Molecular Weight]
357.22 | [MOL File]
1779-49-3.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 1390 4.3/PG 2
| [WGK Germany ]
3
| [Autoignition Temperature]
410 °C | [TSCA ]
T | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29310095 | [Toxicity]
LD50 orally in Rabbit: 118 mg/kg |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Triphenylphosphine-->Methyl bromide | [Preparation Products]
4-Fluorostyrene-->4-Chloro-alpha-methylstyrene-->alpha-cyclopropylstyrene-->Cyclohexene, 2-ethenyl-1,3,3-trimethyl--->9-Decenoic acid, methyl ester-->4-VINYLBENZYL ACETATE-->4-IODOSTYRENE-->Benzoic acid, 2-ethenyl- (9CI)-->2-Hydroxystyrene-->1-Piperidinecarboxylic acid, 3-Methylene-, phenylMethyl ester-->Benzene, 1-ethenyl-2-(1-Methylethoxy)--->P-TRIMETHYLSILYL STYRENE-->4,4'-VINYLIDENEBIS(N,N-DIMETHYLANILINE)-->3-VINYLBENZALDEHYDE-->2-methylenepropane-1,3-diyl diacetate |
| Hazard Information | Back Directory | [Chemical Properties]
white powder | [Uses]
Methyltriphenylphosphonium Bromide is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.
| [Uses]
PTC catalyst | [General Description]
Methyltriphenylphosphoniumbromide is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis.
Mettler-Toledo calibration substance ME 30130598, methyltriphenylphosphoniumbromide is ideal for use in the regular calibration of Mettler-Toledo melting point instrument. Its value is a mean of 6 to 12 iterations with a Mettler-Toledo MP70 Excellence instrument that is calibrated against primary standards. The melting point is validated by Capillary method according to European Pharmacopeia (2.2.14.) | [reaction suitability]
reaction type: C-C Bond Formation | [Purification Methods]
If the solid is sticky, wash it with *C6H6 and dry it in a vacuum over P2O5. [Marvel & Gall J Org Chem 24 1494 1959, Chem Ber 87 1318 1954, Milas & Priesing J Am Chem Soc 79 6295 1957, Wittig & Sch.llkopf Org Synth 40 66 1960.] The iodide, on recrystallisation from H2O, has m 187.5-188.5o [Mann et al. J Chem Soc 1130 1953, Wittig & Geissler Justus Liebigs Ann Chem 580 44 1953]. [Beilstein 16 IV 981.] |
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