| Identification | More | [Name]
3-CHLORO-6-METHOXYPYRIDAZINE | [CAS]
1722-10-7 | [Synonyms]
3-CHLORO-6-METHOXYPYRIDAZINE
SPECS AC-907/25014054
TIMTEC-BB SBB004124
3-Methoxy-6-chloropyridazine
6-Chloro-3-methoxypyridazine
pyridazine, 3-chloro-6-methoxy- | [EINECS(EC#)]
217-019-7 | [Molecular Formula]
C5H5ClN2O | [MDL Number]
MFCD00006467 | [Molecular Weight]
144.56 | [MOL File]
1722-10-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
84-85 °C(lit.)
| [Boiling point ]
285℃ | [density ]
1.292 | [Fp ]
126℃ | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
powder to crystal | [pka]
0.74±0.10(Predicted) | [color ]
White to Almost white | [BRN ]
118854 | [InChI]
InChI=1S/C5H5ClN2O/c1-9-5-3-2-4(6)7-8-5/h2-3H,1H3 | [InChIKey]
XBJLKXOOHLLTPG-UHFFFAOYSA-N | [SMILES]
C1(Cl)=NN=C(OC)C=C1 | [CAS DataBase Reference]
1722-10-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2933998090 |
| Hazard Information | Back Directory | [Uses]
3-Chloro-6-methoxypyridazine was used in the preparation of number of α-aryl-α-(pyridazin-3-yl)-acetonitriles. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 60, p. 1466, 1995 DOI: 10.1021/jo00110a059 | [General Description]
3-Chloro-6-methoxypyridazine undergoes regioselective metallation using various lithium alkylamides, temperatures and solvents (THF and ether). It was lithiated using lithium 2,2,6,6-tetramethylpiperidide during the synthesis of minaprine. |
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