| Identification | More | [Name]
Indole-5-carboxylic acid | [CAS]
1670-81-1 | [Synonyms]
1H-INDOLE-5-CARBOXYLIC ACID
5-CARBOXYINDOLE
5-INDOLECARBOXYLIC ACID
INDOLE-5-CARBOXYLIC ACID
RARECHEM AL BO 0206
TIMTEC-BB SBB003951
INDOLE-5-CARBOXYLIC AICD
Indolecarboxylicacid,5-
Indole-5-carboxylic acid ,98%
5-Carboxy-1H-indole | [EINECS(EC#)]
216-799-6 | [Molecular Formula]
C9H7NO2 | [MDL Number]
MFCD00005678 | [Molecular Weight]
161.16 | [MOL File]
1670-81-1.mol |
| Chemical Properties | Back Directory | [Appearance]
light beige to yellow powder | [Melting point ]
211-213 °C (lit.) | [Boiling point ]
287.44°C (rough estimate) | [density ]
1.2480 (rough estimate) | [refractive index ]
1.5050 (estimate) | [storage temp. ]
−20°C
| [solubility ]
Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol. | [form ]
Powder | [pka]
4.40±0.30(Predicted) | [color ]
Light beige to yellow | [Detection Methods]
HPLC,NMR | [BRN ]
124391 | [InChIKey]
IENZCGNHSIMFJE-UHFFFAOYSA-N | [CAS DataBase Reference]
1670-81-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R21/22:Harmful in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29339990 |
| Hazard Information | Back Directory | [Chemical Properties]
light beige to yellow powder | [Uses]
Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators 1 Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction 2 Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst 3 Reactant for synthesis of indirubin derivatives 4 Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway 5 Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity. | [Definition]
ChEBI: Indole-5-carboxylic acid is an indolecarboxylic acid in which the carboxy group is the only substituent and is located at position 5. It has a role as a plant metabolite. | [General Description]
Indole-5-carboxylic acid is an indole derivative. On electropolymerization, it affords electroactive polymer film of poly(indole-5-carboxylic-acid). Different concentrations of indole-5-carboxylic acid in sulfuric acid solution has been investigated for the preventive action against mild steel corrosion. On electropolymerization it affords a trimeric product. Characterization studies of the trimeric product by 1H NMR and various one- and two-dimensional NMR techniques have been reported. |
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