| Identification | More | [Name]
2-ACETYLCYCLOPENTANONE | [CAS]
1670-46-8 | [Synonyms]
2-ACETYLCYCLOPENTANONE
(R,S)-2-Acetyl-cyclopentanone
2-Acetylcyclopentan-1-one
2-acetyl-cyclopentanon
Acetylcyclopentanone
Cyclopentanone, 2-acetyl-
Cyclopentanone,2-acetyl-
o-acetylcyclopentanone
2-ACETYLCYCLOPENTANONE 98+%
2-Acetylcyclopentanone, GC 99% | [EINECS(EC#)]
216-797-5 | [Molecular Formula]
C7H10O2 | [MDL Number]
MFCD00001413 | [Molecular Weight]
126.15 | [MOL File]
1670-46-8.mol |
| Chemical Properties | Back Directory | [Appearance]
clear light yellow to brown liquid | [Melting point ]
60-70℃ | [Boiling point ]
72-75 °C/8 mmHg (lit.) | [density ]
1.043 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.489(lit.)
| [Fp ]
163 °F
| [storage temp. ]
2-8°C | [form ]
clear liquid | [pka]
10.87±0.20(Predicted) | [color ]
Colorless to Light yellow to Light orange | [Specific Gravity]
1.043 | [BRN ]
1857601 | [LogP]
-0.332 (est) | [CAS DataBase Reference]
1670-46-8(CAS DataBase Reference) | [EPA Substance Registry System]
Cyclopentanone, 2-acetyl- (1670-46-8) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
GY4728000
| [F ]
8-10-23 | [HS Code ]
29142900 |
| Hazard Information | Back Directory | [Chemical Properties]
clear light yellow to brown liquid | [Uses]
2-Acetylcyclopentanone was used to evaluate the protective abilities of 2-ACP in a mouse model of acetaminophen (APAP) hepatotoxicity. | [Purification Methods]
Dissolve the ketone in pet ether (b 30-60o), wash it with saturated aqueous NaHCO3, dry over Drierite and fractionate in a vacuum. It gives a violet colour with ethanolic FeCl3 and is only slowly hydrolysed by 10% aqueous KOH but rapidly on boiling to yield 6-oxoheptanoic acid. [Manyik et al. J Am Chem Soc 75 5030 1953, Acheson J Chem Soc 4232 1956, UV: Martin & Frenelius J Am Chem Soc 81 2342 1959.] It gives a gray green Cu salt from Et2O/pentane, m 237-238o [House & Wasson J Am Chem Soc 79 1488 1957]. |
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