| Identification | More | [Name]
TETRAETHYL METHYLENEDIPHOSPHONATE | [CAS]
1660-94-2 | [Synonyms]
AURORA KA-1506
BIS(DIETHOXYPHOSPHINYL)METHANE
METHYLENEDIPHOSPHONIC ACID TETRAETHYL ESTER
TETRAETHYL(METHYLENE)BISPHOSPHONATE
TETRAETHYL METHYLENEDIPHOSPHONATE
methylenebis(diethylphosphonate)
methylenebis-phosphonicacitetraethylester
methylenedi-phosphonicacitetraethylester
Tetraethyl methylenediphosphonate, 98+%
methanediyl-bis-phosphonic acid tetraethyl ester
Tetraethyl(methylene)bisphosphonate, 98 %
tetraethyl methylenediphosphate
Bis(diethoxyphosphinyl)methane, Methylenediphosphonic acid tetraethylester
[α,β-Methylene]diphosphoric acid tetraethyl
Methylenebis(phosphonic acid diethyl)
Methylenebisphosphonic acid tetraethyl
Methylenedi(phosphonic acid diethyl) ester | [EINECS(EC#)]
216-764-5 | [Molecular Formula]
C9H22O6P2 | [MDL Number]
MFCD00039887 | [Molecular Weight]
288.21 | [MOL File]
1660-94-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,C | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
SZ9150000
| [Hazard Note ]
Corrosive | [TSCA ]
Yes | [HS Code ]
29319090 | [Toxicity]
mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03139, |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow to yellow-brown liquid | [Uses]
Tetraethyl methylidenebisphosphonate, can be used in the synthesis of tetrazoloquinoline-based mono- and bisphosphonate esters as potent anti-inflammatory agents. It is also an intermediate for the synthesis of new bisphosphonate and bisphosphonic acid derivatives with anticancer and antischistosomal activity. | [Synthesis Reference(s)]
Synthetic Communications, 20, p. 1865, 1990 DOI: 10.1080/00397919008053112
Tetrahedron Letters, 34, p. 1515, 1993 DOI: 10.1016/S0040-4039(00)60333-7 | [reaction suitability]
reaction type: C-C Bond Formation |
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