| Identification | Back Directory | [Name]
MI-463 | [CAS]
1628317-18-9 | [Synonyms]
MI-463;MI 463;MI463;1628317-18-9
4-Methyl-5-((4-((6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)meth
1H-Indole-2-carbonitrile, 4-methyl-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]- | [Molecular Formula]
C24H23F3N6S | [MDL Number]
MFCD28506301 | [MOL File]
1628317-18-9.mol | [Molecular Weight]
484.54 |
| Chemical Properties | Back Directory | [Boiling point ]
663.2±55.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble; Ethanol: soluble | [form ]
A crystalline solid | [pka]
14.56±0.30(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
MI-463 is a potent inhibitor of Menin-MLL interaction with IC50 of 15.3 nM. | [target]
| Target | Value | Menin-MLL interaction
(Cell-free assay) | 15.3 nM |
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