成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook--->CAS DataBase List--->160844-75-7

160844-75-7

160844-75-7 Structure

160844-75-7 Structure
IdentificationMore
[Name]

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
[CAS]

160844-75-7
[Synonyms]

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
[EINECS(EC#)]

927-913-5
[Molecular Formula]

C18H20N2O3S
[MDL Number]

MFCD09833701
[Molecular Weight]

344.43
[MOL File]

160844-75-7.mol
Chemical PropertiesBack Directory
[Melting point ]

176 °C
[Boiling point ]

497.1±55.0 °C(Predicted)
[density ]

1.22
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)
[form ]

Solid
[pka]

1.02±0.10(Predicted)
[color ]

White to Off-White
[InChI]

InChI=1S/C18H20N2O3S/c1-5-22-18(21)16-12(4)20-17(24-16)13-6-7-15(14(8-13)9-19)23-10-11(2)3/h6-8,11H,5,10H2,1-4H3
[InChIKey]

OGAZOYHQFBSRMC-UHFFFAOYSA-N
[SMILES]

S1C(C(OCC)=O)=C(C)N=C1C1=CC=C(OCC(C)C)C(C#N)=C1
[CAS DataBase Reference]

160844-75-7(CAS DataBase Reference)
Safety DataBack Directory
[HS Code ]

2934.10.2000
Raw materials And Preparation ProductsBack Directory
[Raw materials]

5-iodo-2-isobutoxybenzonitrile-->ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE-->Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate-->Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate-->Ethyl 2-(3-bromo-4-isobutoxyphenyl)- 4-methyl-5-thiazolecarboxylate-->5-bromo-2-isobutoxy benzonitirle-->3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide-->(3-cyano-4-isobutoxyphenyl)boronic acid-->Febuxostat Impurity 6-->ETHYL 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE-->Ethyl 4-methyl-5-thiazoleactate-->Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate-->5-Bromo-2-fluorobenzonitrile-->1-Bromo-2-methylpropane
[Preparation Products]

Febuxostat
Hazard InformationBack Directory
[Chemical Properties]

White crystalline powder
[Uses]

Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
[Synthesis]

CarboxylatePotassium carbonate (300 g, 2.17 mol) and isobutyl bromide (142.7 g, 1.041 mol) were added to a solution of ethyl-2-(3-cyano-4-hydroxyphenyl)-4-methyl-5-thiazole carboxylate (100 g, 0.347 mol) in dimethylformamide (300 mL), and the reaction mixture was heated at a temperature of about 75°C for about 8 hours. After completion of the reaction, the reaction mixture was cooled to about 40°C, and water was added. The reaction mixture was further cooled to about 0°C and stirred for about 1 hour. The solid thus obtained was filtered, washed with water, and dried to give Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate. (Yield: 11 lg, 92.9%) Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
160844-75-7 suppliers list
Company Name: Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.
Tel: +86-18616643091 +86-18616643091 , +86-18616643091
Website:
Company Name: JUYE XIANDAI fine chemistry Co.,Ltd
Tel: +86-18958038633; +8618958038633 , +8618958038633
Website: http://www.is0513.com/ShowSupplierProductsList1077666/0.htm
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-29-81148696 +86-15536356810 , +86-15536356810
Website: http://www.is0513.com/manufacturer/shaanxi-dideu-medichem-221/
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +86 13288715578 +8613288715578 , +8613288715578
Website: http://www.mojinchemical.com
Company Name: Hebei Yanxi Chemical Co., Ltd.
Tel: +8617531190177 , +8617531190177
Website: www.is0513.com/manufacturer/hebei-yanxi-chemical-283/
Company Name: Zibo Hangyu Biotechnology Development Co., Ltd
Tel: +86-0533-2185556 +8617865335152 , +8617865335152
Website: www.is0513.com/manufacturer/hangyu-chemical-25178/
Company Name: Anhui Ruihan Technology Co., Ltd
Tel: +8617756083858 , +8617756083858
Website: www.is0513.com/manufacturer/anhui-ruihan-technology/
Company Name: ShenZhen H&D Pharmaceutical Technology Co., LTD
Tel: +8618627948422 , +8618627948422
Website: www.hdimpurity.com/
Company Name: HEBEI BRANT PHARMACEUTICAL CO.,LTD
Tel: +86-311-84455288 +86-18832137600 , +86-18832137600
Website: www.brantpharm.com
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-(0)57185586718 +86-13336195806 , +86-13336195806
Website: www.capot.com
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Website: https://www.dakenchem.com/
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd
Tel: 010-60279497
Website: http://www.cooperate-pharm.com
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512 , +86-19937530512
Website: https://www.tianfuchem.com/
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: +8615858145714 , +8615858145714
Website: www.fandachem.com/
Company Name: Nanjing Finetech Chemical Co., Ltd.
Tel: 025-85710122 17714198479
Website: www.fine-chemtech.com
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: Zhejiang ZETian Fine Chemicals Co. LTD
Tel: +8618957127338 , +8618957127338
Website: www.zetchem.com/
Company Name: SHANDONG ZHI SHANG CHEMICAL CO.LTD
Tel: +86 18953170293 , +86 18953170293
Website: https://www.zhishangchem.com/
Tags:160844-75-7 Related Product Information
19982-08-2 161798-02-3 161798-01-2 1351692-92-6 1206550-99-3 144060-53-7 161798-03-4 161797-99-5 1346238-10-5 1271738-74-9 1330632-48-8 1239233-87-4 1530308-87-2 144060-62-8 1330632-46-6 528607-60-5 100118-38-5 1229019-33-3