Identification | More | [Name]
1-ACETYLINDOLINE | [CAS]
16078-30-1 | [Synonyms]
1-(2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE 1-(2,3-DIHYDRO-INDOL-1-YL)-ETHANONE 1-ACETYL-2,3-DIHYDROINDOLE 1-ACETYLINDOLINE N-ACETYL INDOLINE 1-acetyl-2,3-dihydro-1h-indol 1-acetyl-indolin Acetylindoline,N- 1H-Indole, 1-acetyl-2,3-dihydro-(9CI) 1-ACETYLINDOLINE 98+% 1-Acetyl-2,3-dihydro-1H-indole | [Molecular Formula]
C10H11NO | [MDL Number]
MFCD00022908 | [Molecular Weight]
161.2 | [MOL File]
16078-30-1.mol |
Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
NM1892500
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Hazard Information | Back Directory | [Uses]
• ;Reactant for preparation of triazolothiadiazepine dioxide derivatives1• ;Reactant for preparation of halo-substituted aromatic amides2• ;Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists3• ;Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents4• ;Reactant for regioselective ortho Suzuki-Miyaura coupling reaction5 | [Uses]
- Reactant for preparation of triazolothiadiazepine dioxide derivatives
- Reactant for preparation of halo-substituted aromatic amides
- Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists
- Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents
- Reactant for regioselective ortho Suzuki-Miyaura coupling reaction
| [Uses]
1-(2,3-Dihydroindol-1-yl)ethanone is an intermediate used for preparation of triazolothiadiazepine dioxide derivatives, halo-substituted aromatic amides and [[(phenyl)piperazinyl]alkyl]indolyl]ethanone. | [Synthesis Reference(s)]
Tetrahedron, 52, p. 7525, 1996 DOI: 10.1016/0040-4020(96)00266-9 Tetrahedron Letters, 24, p. 561, 1983 DOI: 10.1016/S0040-4039(00)81464-1 | [General Description]
1-Acetylindoline, a substituted indole, is a tertiary amide having bulky N-groups. Its reduction to the corresponding amine, by reaction with silane in the presence of MoO2Cl2 (catalyst), has been reported. |
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