| Identification | More | [Name]
(S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL | [CAS]
15914-84-8 | [Synonyms]
(S)-(-)-1-(1-NAPHTHYL)ETHANOL
(S)-1-NAPHTHALEN-1-YL-ETHANOL
(S)-(-)-ALPHA-METHYL-1-NAPHTHALENEMETHANOL
(s)-(-)-α-methyl-1-naphthalenemethanol
s-(-)-α-methyl-1-naphthalenemethanol
S-(-)-1-(1-NAPTHALENYL)ETHANOL
(S)-1-Naphthylethanol
(1S)-1-(1-Naphthyl)ethanol
(S)-α-Methylnaphthalenemethanol
(αS)-α-Methylnaphthalene-1-methanol
(S)-(-)-1-(1-Naphtyl)ethanol | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C12H12O | [MDL Number]
MFCD00077831 | [Molecular Weight]
172.22 | [MOL File]
15914-84-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
47-49 °C(lit.)
| [alpha ]
-77 º (C=1 IN MEOH) | [Boiling point ]
165°C/11mmHg(lit.) | [density ]
1.113±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Powder | [pka]
14.29±0.20(Predicted) | [color ]
Yellow | [optical activity]
[α]20/D 77°, c = 1 in methanol | [BRN ]
2045009 | [CAS DataBase Reference]
15914-84-8(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White fine crystalline powder | [Uses]
(S)?-?1-?(Naphthalen-?1-?yl)?ethanol is a building block used in the synthesis of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy. | [Purification Methods]
Purify the alcohol by recrystallisation from Et2O/pet ether, Et2O, hexane [Balfe et al. J Chem Soc 797 1946, IR, NMR: Theisen & Heathcock J Org Chem 53 2374 1988, see also Fredga et al. Acta Chem Scand 11 1609 1957]. The RS-alcohol [57605-95-5] has m 63-65o, 65-66o from hexane. [Beilstein 6 III 3034, 6 IV 4346.] |
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