| Identification | More | [Name]
4-Methylbenzenesulfonhydrazide | [CAS]
1576-35-8 | [Synonyms]
4-METHYL-1-BENZENESULFONYL HYDRAZIDE
4-Methylbenzenesulfonhydrazide
4-METHYLBENZENESULFONYL HYDRAZIDE
4-TOLUENESULFONIC ACID HYDRAZIDE
4-TOLUENESULFONOHYDRAZIDE
4-TOLUENESULFONYL HYDRAZIDE
LABOTEST-BB LT00071719
P-TOLUENESULFONHYDRAZIDE
P-TOLUENESULFONIC ACID HYDRAZIDE
P-TOLUENESULFONYL HYDRAZIDE
P-TOLUENESULFONYLHYDRAZINE
P-TOLUENESULPHONYL HYDRAZIDE
P-TOLYL HYDRAZIDE
P-TOLYLSULFONYLHYDRAZINE
SPECS AC-907/25014186
TOLUENE-4-SULFONIC ACID HYDRAZIDE
TOLUENE-4-SULFONOHYDRAZIDE
TOLUENE-4-SULPHONHYDRAZIDE
toluene-4-sulphonohydrazide
TOSYLHYDRAZIDE | [EINECS(EC#)]
216-407-3 | [Molecular Formula]
C7H10N2O2S | [MDL Number]
MFCD00007588 | [Molecular Weight]
186.23 | [MOL File]
1576-35-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white to off-white powder | [Melting point ]
103-108 °C(lit.)
| [Boiling point ]
340.5±35.0 °C(Predicted) | [density ]
1.42g/cm3 | [vapor pressure ]
0Pa at 20℃ | [refractive index ]
1.5400 (estimate) | [Fp ]
60°C | [storage temp. ]
Flammables area | [solubility ]
5g/l | [form ]
Powder | [pka]
9.39±0.10(Predicted) | [color ]
White or off-white to slightly grayish | [Water Solubility ]
5 g/L (15 ºC) | [Sensitive ]
Moisture Sensitive | [Detection Methods]
HPLC,NMR,MS | [BRN ]
610130 | [Stability:]
Light Sensitive | [InChIKey]
ICGLPKIVTVWCFT-UHFFFAOYSA-N | [LogP]
0.55 at 25℃ | [CAS DataBase Reference]
1576-35-8(CAS DataBase Reference) | [Storage Precautions]
Store under nitrogen | [EPA Substance Registry System]
1576-35-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn | [Risk Statements ]
R11:Highly Flammable.
R22:Harmful if swallowed.
R44:Risk of explosion if heated under confinement. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 3226 4.1
| [WGK Germany ]
3
| [RTECS ]
MW0210000
| [TSCA ]
Yes | [HazardClass ]
4.1 | [PackingGroup ]
II | [HS Code ]
29280090 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white powder | [Application]
p-Toluenesulfonyl hydrazide is used as a reagent for the preparation of tosylhydrazones. It was used to prepare dipyrazolo[1,5-a:4',3'-c]pyridines and 1,2,3-selenadiazole derivatives. | [Reactions]
4-Methylbenzenesulfonhydrazide as hydrogen donor in reduction reactions: A base-mediated semihydrogenation of ynamides using 4-Methylbenzenesulfonhydrazide (p-toluenesulfonyl
hydrazide) as an inexpensive and easy-to-handle hydrogen donor provides the
thermodynamically unfavorable Z-enamides exclusively without
overhydrogenation and reduction of other functional groups. | [Flammability and Explosibility]
Notclassified | [Purification Methods]
Dissolve the hydrazide in hot MeOH (~1g/4mL), filter through Celite and precipitate the material by adding 2-2.5 volumes of distilled H2O. Dry it in air or in a vacuum. [Fiedman et al. Org Synth Coll Vol V 1055 1973, Beilstein 11 II 66.] |
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