| Identification | Back Directory | [Name]
Urea, N-[(3R)-5-cyclohexyl-2,3-dihydro-1-methyl-2-oxo-1H-1,4-benzodiazepin-3-yl]-N'-[3-(methyl-1H-tetrazol-5-ylamino)phenyl]- (9CI) | [CAS]
152885-49-9 | [Synonyms]
L736
L-736
L 736
L736380
L-736380
L 736380
Urea, N-[(3R)-5-cyclohexyl-2,3-dihydro-1-methyl-2-oxo-1H-1,4-benzodiazepin-3-yl]-N'-[3-(methyl-1H-tetrazol-5-ylamino)phenyl]- (9CI) | [Molecular Formula]
C25H29N9O2 | [MOL File]
152885-49-9.mol | [Molecular Weight]
487.56 |
| Hazard Information | Back Directory | [Description]
L-736380, also known as L-736,380, is a CCK-B receptor antagonist. L-736,380 dose-dependently inhibited gastric acid secretion in anesthetized rats (ID(50), 0.064 mg/kg) and ex vivo binding of [(125)I]CCK-8S in BKTO mice brain membranes (ED(50), 1.7 mg/kg) and is one of the most potent acidic CCK-B receptor antagonists yet described. |
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