| Identification | More | [Name]
SAQUINAVIR MESYLATE | [CAS]
149845-06-7 | [Synonyms]
FORTOVASE
INVIRASE
RO 31-8959
SAQUINAVIR MESYLATE
(2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide Mesylate
Ro 31-895
Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, monomethanesulfonate (salt) (9CI)
Butanediamide, N1-[3-[3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, [3S-[2[1R*(R*),2S*],3a,4ab,8ab]]-, monomethanesulfonate (salt)
Ro 31-8959/003 | [Molecular Formula]
C39H54N6O8S | [MDL Number]
MFCD00944907 | [Molecular Weight]
766.95 | [MOL File]
149845-06-7.mol |
| Safety Data | Back Directory | [WGK Germany ]
3 | [HS Code ]
2933492250 | [Toxicity]
monkey,LD,oral,> 1680mg/kg (1680mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 2183, 1998. |
| Hazard Information | Back Directory | [Hazard]
Moderately toxic by ingestion. | [Chemical Properties]
White Crystalline Solid | [Uses]
Saquinavir mesylate may be used in cell signaling and immunology studies. | [Uses]
A selective HIV protease inhibitor. Antiviral. | [Uses]
Antiviral;Protease inhibitor | [Definition]
ChEBI: Saquinavir mesylate is an organic molecular entity. | [Brand name]
Invirase (Roche). | [General Description]
Saquinavir is a peptidomimetic hydroxyethylamine inhibitor, which is used to treat human immunodeficiency virus (HIV) infection. | [Biochem/physiol Actions]
Saquinavir is an HIV Protease Inhibitor used in antiretroviral therapy. It inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at saquinavir as a possible anti-cancer agent. | [storage]
Store at +4°C |
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