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ChemicalBook--->CAS DataBase List--->149249-91-2

149249-91-2

149249-91-2 Structure

149249-91-2 Structure
IdentificationMore
[Name]

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone
[CAS]

149249-91-2
[Synonyms]

(3R,4S)-1-BENZOYL-3-[(TRIETHYLSILYL)OXY]-4-PHENYL-2-AZETIDINONE
(3r,4s)-1-benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone
(+)-cis-1-Benzoyl-3-triethylsilyloxy-4-phenyl-2-azetidinone
PACLITAXEL SIDE CHAIN NO 2
(3R,4S)-1-Benzoyl-4-Phenyl-3-[(Triethylsilyl)Oxy]-2-AzetidinoneCasNo.
(3R,4S)-1-BENZOYL-3-[(TRIETHYLSILYS)OXY]-4-PHENYL-2-AZETIDINONE
(3R,4S)-1-Benzoyl-3-[(Triethyl
PACLITAXEL SIDE CHAIN/(3R,4S)-1-BENZOYL-3-[(TRIETHYLSILYL)OXY]-4-PHENYL-2-PHENYL-2-AZETIDINONE
(+)-cis-1-Benzoyl-3-triethylsilyloxy-4-phenyl-2-azetidinone
[Molecular Formula]

C22H27NO3Si
[MDL Number]

MFCD08273950
[Molecular Weight]

381.54
[MOL File]

149249-91-2.mol
Chemical PropertiesBack Directory
[Boiling point ]

467.2±55.0 °C(Predicted)
[density ]

1.12
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

Dichloromethane, Ether, Ethyl Acetate, Methanol
[form ]

Oil
[pka]

-4.66±0.60(Predicted)
[color ]

Transparent
[CAS DataBase Reference]

149249-91-2(CAS DataBase Reference)
Hazard InformationBack Directory
[Uses]

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone is an intermedaite of 10-O-[(2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel (B207800), which is an impurity in the synthesis of Paclitaxel (P132500), an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi''s sarcoma.
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

149249-91-2(sigmaaldrich)
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