| Identification | Back Directory | [Name]
(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine | [CAS]
147116-67-4 | [Synonyms]
Maropitant
(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
(2S,3S)-2-(Diphenylmethyl)-N-[2-methoxy-5-(2-methyl-2-propanyl)benzyl]quinuclidin-3-amine
(2S-cis)-N-[[5-(1,1-DiMethylethyl)-2-Methoxyphenyl]Methyl]-2-(diphenylMethyl)-1-azabicyclo[2.2.2]octan-3-aMine
1-Azabicyclo[2.2.2]octan-3-amine, N-[[5-(1,1-dimethylethyl)-2-methoxyphenyl]methyl]-2-(diphenylmethyl)-, (2S,3S)- | [EINECS(EC#)]
201-069-1 | [Molecular Formula]
C32H40N2O | [MDL Number]
MFCD25541735 | [MOL File]
147116-67-4.mol | [Molecular Weight]
468.673 |
| Chemical Properties | Back Directory | [Boiling point ]
572.6±50.0 °C(Predicted) | [density ]
1.11±0.1 g/cm3(Predicted) | [vapor pressure ]
0-0Pa at 20-25℃ | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 33.33 mg/mL (71.12 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | [form ]
Solid:particulate/powder | [pka]
9.99±0.70(Predicted) | [color ]
Off-white to yellow | [LogP]
3.1-7.2 at pH2-7.5 | [CAS DataBase Reference]
147116-67-4 |
| Hazard Information | Back Directory | [Uses]
Maropitant is a neurokinin type 1 (NK-1) receptor antagonist. Recent studies show that Maropitant decreased the anesthetic requirements during visceral stimulation of the ovary and ovarian ligament in dogs. | [Biological Activity]
Maropitant is a neurokinin-1 receptor (NK-1R) antagonist with in vivo antiemetic efficacy. | [storage]
Store at -20°C |
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