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ChemicalBook--->CAS DataBase List--->1446090-79-4

1446090-79-4

1446090-79-4 Structure

1446090-79-4 Structure
IdentificationBack Directory
[Name]

5-((1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
[CAS]

1446090-79-4
[Synonyms]

EOS-60483
Lifirafenib
Beigene-283
BGB-283;BEIGENE-283
5-((1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
1,8-Naphthyridin-2(1H)-one, 5-[[(1R,1aS,6bR)-1a,6b-dihydro-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1H-cyclopropa[b]benzofuran-5-yl]oxy]-3,4-dihydro-
[Molecular Formula]

C25H17F3N4O3
[MDL Number]

MFCD30489379
[MOL File]

1446090-79-4.mol
[Molecular Weight]

478.42
Chemical PropertiesBack Directory
[Boiling point ]

651.9±65.0 °C(Predicted)
[density ]

1.72±0.1 g/cm3(Predicted)
[solubility ]

DMSO:97.5(Max Conc. mg/mL);203.79(Max Conc. mM)
Ethanol:95.0(Max Conc. mg/mL);198.57(Max Conc. mM)
[form ]

Solid
[pka]

10.16±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Lifirafenib it is quinoline derivative used for combination treatment of small cell lung cancer.
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