| Identification | More | [Name]
L-4-Chlorophenylalanine | [CAS]
14173-39-8 | [Synonyms]
4-Chloro-3-phenyl-L-alanine
4-CHLORO-L-PHENYLALANINE
4-CHLORO-PHENYLALANINE
4-CHLORO-PHE-OH
H-L-PHE(4-CL)-OH
H-P-CHLORO-L-PHE-OH
H-P-CHLORO-PHE-OH
H-PHE(4-CL)-OH
H-PHE(PCL)-OH
L-4-CHLOROPHE
L-4-CHLOROPHENYLALANINE
L-P-CHLOROPHENYLALANINE
L-PCP
L-PCPA
L-PHE(4-CL)
P-CHLORO-L-PHENYLALANINE
P-CHLORO-PHENYLALANINE
RARECHEM BK PT 0013
(S)-2-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID
3-(4-Chlorophenyl)-L-alanine | [EINECS(EC#)]
238-023-5 | [Molecular Formula]
C9H10ClNO2 | [MDL Number]
MFCD00063065 | [Molecular Weight]
199.63 | [MOL File]
14173-39-8.mol |
| Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
263 °C (dec.)(lit.) | [alpha ]
-27 º (c=0.5, H2O 34 ºC) | [Boiling point ]
339.5±32.0 °C(Predicted) | [density ]
1.2409 (rough estimate) | [refractive index ]
1.5790 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
Aqueous Base (Slightly), Water (Slightly) | [form ]
Powder | [pka]
2.18±0.10(Predicted) | [color ]
White | [Water Solubility ]
Soluble in acetic acid. Slightly soluble in water. | [BRN ]
2416150 | [InChIKey]
NIGWMJHCCYYCSF-QMMMGPOBSA-N | [CAS DataBase Reference]
14173-39-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T,Xi | [Risk Statements ]
R25:Toxic if swallowed.
R43:May cause sensitization by skin contact. | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [HazardClass ]
6.1 | [PackingGroup ]
Ⅲ | [HS Code ]
29224999 |
| Hazard Information | Back Directory | [Chemical Properties]
white powder | [Uses]
4-Chloro-L-phenylalanine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals. | [Definition]
ChEBI: A non-proteinogenic L-alpha-amino acid that is L-phenylalanine in which the meta-hydrogen of the phenyl group has been replaced by a chlorine. | [Biochem/physiol Actions]
4-Chloro-L-phenylalanine (L-PCPA) inhibits the synthesis of 5-hydroxytryptamine (5-HT). 4-Chloro-DL-phenylalanine (PCPA) depletes the serotonin levels in the brain by its inhibitory effect on tryptophan hydroxylase (Tph). Studies support the protective effects of PCPA against monocrotaline-induced pulmonary vascular remodeling as well as in lung inflammation. |
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