Identification | More | [Name]
alpha-Hydroxybenzenepropanoic acid methyl ester | [CAS]
13673-95-5 | [Synonyms]
(-)-3-phenyllactic acid methyl ester alpha-Hydroxybenzenepropanoic acid methyl ester l-3-phenyl-lactic acid methyl ester L-BETA-PHENYLLACTIC ACID-OME L-METHYL 3-PHENYLLACTATE L-METHYL-BETA-PHENYLLACTATE L(-) PHENYLLACTIC ACID METHYL ESTER METHYL L-3-PHENYLLACTATE METHYL (S)-2-HYDROXY-3-PHENYLPROPIONATE (S)-2-HYDROXY-3-PHENYL-PROPIONIC ACID-METHYL ESTER (S)-3-PHENYLLACTIC ACID, METHYL ESTER (-)-3-Phenyllactic acid methyl ester L-b-Phenyllactic acid-OMe (-)-3-Phenyl-L-lactic acid methyl ester (2S)-2-Hydroxy-3-phenylpropionic acid methyl ester (S)-3-Phenyl-2-hydroxypropionic acid methyl ester | [Molecular Formula]
C10H12O3 | [MDL Number]
MFCD00038224 | [Molecular Weight]
180.2 | [MOL File]
13673-95-5.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
40-45 °C (lit.) | [alpha ]
-20.0 º(c=2,H2O) | [Boiling point ]
110-115 °C(Press: 3 Torr) | [density ]
1.150 | [Fp ]
120°C | [storage temp. ]
2-8°C | [pka]
13.00±0.20(Predicted) | [optical activity]
[α]/D +4.4±0.5°, c = 1% in methanol | [CAS DataBase Reference]
13673-95-5(CAS DataBase Reference) |
Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
Methyl?L-3-phenyllactate can be used:
- As an intermediate in the synthesis of bortezomib analogs as 20S proteasome inhibitors.
- As a substrate in the amination of the benzylic C-H bonds and the aminated products are further used to prepare β-lactams.
- As an intermediate in one of the key synthetic steps for the preparation of YM-254890 analog, a selective Gαq/11 inhibitor.
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