| Identification | Back Directory | [Name]
TYRPHOSTIN AG 835 | [CAS]
133550-37-5 | [Synonyms]
AG 835
TYRPHOSTIN B50
(+)-Enantiomer
TYRPHOSTIN B50(+)
TYRPHOSTIN AG 835
(+)-Tyrphostin B44
TYRPHOSTIN B44, (+) ENANTIOMER
Tyrphostin B44, (+) enantiomer AG835
(S)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide
ALPHA-CYANO-(+)-(S)-N-(ALPHA-PHENETHYL)-(3,4-DIHYDROXY)CINNAMIDE
(+)-(s)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
(+)-(S)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide
(2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-[(1S)-1-Phenylethyl]-2-Propenamide
(S)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE
2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-, (2E)-
Tyrphostin B50, (+)-(S)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
non-metastatic tumors,INBL,antitumor,(+)-Tyrphostin B44,Epidermal growth factor receptor,Tyrphostin B50,ErbB-1,Tyrphostin B-44, (+) enantiomer,Inhibitor,Tyrphostin B 50,CALO,cervical carcinoma cell,EGFR,inhibit,Tyrphostin B44, (+) enantiomer,Tyrphostin AG835,HER1,Tyrphostin AG-835,Tyrphostin AG 835,Tyrphostin B-50 | [Molecular Formula]
C18H16N2O3 | [MDL Number]
MFCD00209855 | [MOL File]
133550-37-5.mol | [Molecular Weight]
308.33 |
| Chemical Properties | Back Directory | [Melting point ]
146 °C | [storage temp. ]
−20°C
| [solubility ]
DMSO or ethanol: soluble
| [form ]
powder to crystal | [color ]
Light yellow to Amber to Dark green |
| Hazard Information | Back Directory | [Uses]
Tyrphostin B44, (+) enantiomer is an EGFR kinase inhibitor. | [Biological Activity]
Epidermal growth factor receptor (EGFR) kinase inhibitor (IC 50 = 0.86 μ M). Slightly less active than the (-) enantiomer ((R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). | [storage]
Store at -20°C |
|
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
3A Chemicals
|
| Tel: |
400-668-9898 |
| Website: |
www.3achem.com |
| Company Name: |
BOC Sciences
|
| Tel: |
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| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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