Identification | Back Directory | [Name]
4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine | [CAS]
123148-78-7 | [Synonyms]
EOS-62121 6-Chloro-7-iodo-deazapurine 4-Chloro-5-iodo-1H-pyrrol... 6-Chloro-7-iodo-7-deazapurine 6-Chloro-7-iodo-7-deazapurine > 6-Chloro-7-iodo-7-deazapurine,96% 4-CHLORO-5-IODO-7H-PYRROL[2,3]PYRIMIDINE 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine 5-Iodo-4-chloro-7H-pyrrol[2,3-d]pyrimidine 4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine 4-CHLORO-5-IODO-1H-PYRROLO [2,3-D] PYRIMIDINE 7H-Pyrrolo[2,3-d]pyriMidine, 4-chloro-5-iodo- JR-13973, 4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine, 95% 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine ISO 9001:2015 REACH 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine
6-Chloro-7-iodo-7-deazapurine | [EINECS(EC#)]
626-377-7 | [Molecular Formula]
C6H3ClIN3 | [MDL Number]
MFCD09263258 | [MOL File]
123148-78-7.mol | [Molecular Weight]
279.47 |
Chemical Properties | Back Directory | [Melting point ]
179-183 °C | [Boiling point ]
241.0±50.0 °C(Predicted) | [density ]
2.47±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
9.61±0.20(Predicted) | [color ]
White to Orange to Green | [Water Solubility ]
Insoluble in water. | [Sensitive ]
Light Sensitive | [λmax]
305nm(H2O)(lit.) | [InChIKey]
CBWBJFJMNBPWAL-UHFFFAOYSA-N |
Hazard Information | Back Directory | [Uses]
6-Chloro-7-iodo-7-deazapurine is used as pharmaceutical intermediate. | [Definition]
4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine, also known as 6-Chloro-7-iodo-7-deazapurine or 4-Chloro-5-iodo-1H-pyrrolo[2,3-d]pyrimidine, is a white solid that can be obtained by iodine reaction of 4-chloro-7h-pyrrole [2,3-d] pyrimidine with NIS.
| [Synthesis]
4-chloro-7h-pyrrole [2,3-d] pyrimidine (8.0 g, 52.32 mmol, 1.0 eq) was dissolved in DMF(40 mL) and NIS(15.7g, 57.55 mmol, 1.1eq) was added at 0℃. After stirring at room temperature overnight, 200 mL of saturated Na2S2O3 solution was added. The mixture was filtered, washed with water three times, and vacuum drying, to obtain 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine.
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