| Identification | More | [Name]
Triisopropanolamine | [CAS]
122-20-3 | [Synonyms]
1,1',1''-NITRILOTRI-2-PROPANOL
1,1',1''-NITRILOTRIPROPAN-2-OL
1,1',1''-NITRILOTRIS(2-PROPANOL)
1,1',1''-NITROLOTRIPROPAN-2-OL
AMIX TI
NITRILOTRIPROPANOL
TRIISOPROPANOLAMINE
TRIS(2-HYDROXYPROPYL)AMINE
1,1',1-Nitrilopropan-2-ol
1,1’,1’’-nitrilotri-2-propano
1,1’,1’’-nitrilotris-2-propano
2-Propanol, 1,1',1''-nitrilotri-
2-Propanol,1,1’,1’’-nitrilotris-
3,3',3-Nitrilotri(2-propanol)
78-96-6
78-96-61,1’,1’’-
78-96-61,1’,1’’-nitrilotripropan-2-ol
78-96-61,1’,1’’-nitrilotripropan-2-ol/1-aminopropan-2-ol
Tri-2-propanolamine
Tripropanolamine | [EINECS(EC#)]
204-528-4 | [Molecular Formula]
C9H21NO3 | [MDL Number]
MFCD00004533 | [Molecular Weight]
191.27 | [MOL File]
122-20-3.mol |
| Chemical Properties | Back Directory | [Appearance]
white to slightly yellow crystalline low | [Melting point ]
48-52 °C (lit.) | [Boiling point ]
190 °C/23 mmHg (lit.) | [density ]
1.0 | [vapor pressure ]
1 hPa (100 °C) | [refractive index ]
1.4200 (estimate) | [Fp ]
160 °C
| [storage temp. ]
Store below +30°C. | [form ]
Crystalline Low Melting Solid | [pka]
14.37±0.20(Predicted) | [color ]
White to slightly yellow | [PH]
10.8 (100g/l, H2O, 20℃) | [explosive limit]
0.8-5.8%(V) | [Water Solubility ]
Soluble | [FreezingPoint ]
52℃ | [Sensitive ]
Hygroscopic | [BRN ]
1071570 | [LogP]
-0.015 at 23℃ | [Uses]
Emulsifying agents. | [CAS DataBase Reference]
122-20-3(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Propanol, 1,1',1''-nitrilotris-(122-20-3) | [EPA Substance Registry System]
122-20-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36:Irritating to the eyes.
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 3259 8/PG 2
| [WGK Germany ]
1
| [RTECS ]
UB8750000
| [Autoignition Temperature]
275 °C | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29221990 | [Hazardous Substances Data]
122-20-3(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 4000 mg/kg LD50 dermal Rabbit 10000 mg/kg |
| Hazard Information | Back Directory | [General Description]
White solid with slight odor of ammonia. Denser than water . | [Reactivity Profile]
TRIISOPROPANOLAMINE(122-20-3) neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by combination with strong reducing agents, such as hydrides. | [Air & Water Reactions]
Water soluble | [Health Hazard]
Irritation of eyes and skin. May cause slight corneal injury or burn. Repeated contact may cause skin burn. Heated vapor may cause moderate respiratory irritation. Low to moderately toxic by oral routes. | [Description]
Triisopropanolamine (TIPA), a tertiary alkanolamine, is majorly used as a grinding chemical that reduces agglomeration in the ball milling process and changes the particle distribution of the finished cement. | [Chemical Properties]
Triisopropanolamine is a corrosive and hygroscopic
solid. | [Chemical Properties]
white to slightly yellow crystalline low | [Application]
Triisopropanolamine (TIPA) can act as an interfacial transition zone (ITZ) to improve the mechanical properties of the mortar and the concrete. It can also be used to increase the compressive strength of the cement-fly ash system by accelerating the hydration of both the compounds.
1. Cement industry - TIPA is commonly used a cement grinding additives. It increases the strength of cement and other mixtures for cement.
2. Metallurgy - TIPA is used as antioxidants and coolant and prevent corrosion in metals.
3. Polyurethane industry - preliminary usage as a agent and catalyst to improve PU quality.
4. Textile industry - TIPA is used as refining agent and other dye specific agent properties. | [Definition]
ChEBI: Triisopropanolamine is an amino alcohol. | [Hazard]
Irritant to skin and eyes. | [Flammability and Explosibility]
Nonflammable | [Toxicity evaluation]
Diisopropanolamine, Triisopropanolamine, Isopropanolamine, and Mixed Isopropanolamine are used as water-soluble emulsifiers and neutralizers in cosmetic products at concentrations up to 1%. In animal studies these ingredients were slightly toxic to practically nontoxic to rats and guinea pigs via acute oral administration. Triisopropanolamine was relatively nontoxic to rats in the two subchronic oral studies. These ingredients were moderate skin irritants for rabbits. All four ingredients, when tested at 100% concentrations, were severe ocular irritants in rabbits. Products containing small amounts (-1%) of Diisopropanolamine or Triisopropanolamine were not ocular irritants in rabbits. The Triisopropanolamine salt was not mutagenic in Aspergillus nidulans. Diisopropanolamine and Isopropanolamine at concentrations of 2% did not induce allergic contact dermatitis or photoallergic dermatitis in humans. Clinical studies on cosmetic products containing no more than 1% Diisopropanolamine or 1.1% Triisopropanolamine were minimal skin irritant and contact sensitizers. It is concluded that Diisopropanolamine, Triisopropanolamine, Isopropanolamine, and Mixed Isopropanolamine are safe as cosmetic ingredients in the present practices of use and concentration. The Isopropanolamines should not be used in products containing N-nitrosating agents.
Final Report on the Safety Assessment of Diisopropanolamine, Triisopropanolamine, Isopropanolamine, and Mixed Isopropanolamine | [Precautions]
Hygroscopic. Store away from oxidizing agents, water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. | [References]
Pensri Piboonchaisit, et al. Novel Route to Tris(silatranyloxy-i-propyl)amine Directly from Silica and Triisopropanolamine, Part I.ScienceAsia.1999,25113-119.
Paul J. Sandberg.; F. Doncaster. On the mechanism of strength enhancement of cement paste and mortar with triisopropanolamine.Cem. Concr. Res.2004,34(6), 973-976. |
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