| Identification | More | [Name]
Premarin | [CAS]
12126-59-9 | [Synonyms]
CONJUGATED ESTROGEN
CONJUGATED ESTROGENS
ESTROGENS, CONJUGATED
cee
climestrone
co-estro
conest
conestron
conjes
conjugatedequineestrogen
conjugatedestrogenichormones
conjutabs
equigyne
estratab
estrifol
estroate
estrocon
estrogens,conjugates
estromed
estropan | [EINECS(EC#)]
235-199-5 | [Molecular Formula]
C18H19NaO5S | [MDL Number]
MFCD00240712 | [Molecular Weight]
370.4 | [MOL File]
12126-59-9.mol |
| Hazard Information | Back Directory | [Potential Exposure]
Conjugated estrogens are naturally occurring substances excreted in the urine of pregnant mares; piperazine estrone sulfate is not known to occur naturally. Conjugated estrogens are used to treat symptoms of the climacteric, vulvae dystrophies; female hypogonadism; and dysfunctional uterine bleeding. They also are used for treatment following: ovariectomy, for chemotherapy of mammary cancer and prostate carcinogema; and for prevention of postpartum breast engorgement. In addition, conjugated estrogens have been found in cosmetic preparations | [First aid]
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. | [Shipping]
UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required. UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials. PGIII. | [Incompatibilities]
Estrogens are Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid chlorides, and acid anhydrides. | [Description]
Conjugated estrogens generally occur as butter-colored powders that are soluble in water. The sodiumequilin sulfate component is unstable to light and air.Piperazine estrone sulfate occurs as a white to yellowishwhite crystalline powder that is slightly soluble in water.Piperazine estrone sulfate melts at 245℃ with decomposition. Conjugated estrogens are naturally occurring substances excreted in the urine of pregnant mares; piperazineestrone sulfate is not known to occur naturally. | [Chemical Properties]
Almost white or brownish, amorphous powder. | [Chemical Properties]
Conjugated estrogens generally occur as butter-colored powders | [Waste Disposal]
It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged, and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator | [Definition]
ChEBI:Equilin sodium sulfate is a steroid sulfate. It is functionally related to an equilin. | [storage]
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045. |
| Safety Data | Back Directory | [Safety Profile]
Suspected human
carcinogen producing tumors of the vascular
system and liver. Human reproductive
effects: changes in female fertility. When
heated to decomposition it emits toxic
fumes of NazO. See also indvidual
components. |
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