Identification | More | [Name]
4-Chloro-N-(4-tert-butylbenzyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide | [CAS]
119168-77-3 | [Synonyms]
4-CHLORO-5-ETHYL-2-METHYL-N-[(4-TERT-BUTYLPHENYL)METHYL]PYRAZOLE-3-CARBOXAMIDE 4-CHLORO-N-(4-TERT-BUTYLBENZYL)-3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXAMIDE COMANCHE MASAI OSCAR PYRANICA TEBUFENPYRAD 1h-pyrazole-5-carboxamide,4-chloro-n-((4-(1,1-dimethylethyl)phenyl)methyl)-3-e 4-chloro-n-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1h-pyrazol 4-chloro-n-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1h-pyrazole-5-carboxamid ac801757 e-5-carboxamide mk239 n-(4-t-butylbenzyl)-4-chloro-3-ethyl-1-methylpyrazole-5-carboxamide thyl-1-methyl- 4-chloro-N-(4-(1,1-dimethylethyl)phenyl)methyl-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-5-pyrazolemethylamide comanché tebufenpyrad (bsi,draft-iso) Sandoz Pyranica Selective Miticide******OBSOLETE********** | [EINECS(EC#)]
242-070-7 | [Molecular Formula]
C18H24ClN3O | [MDL Number]
MFCD01632408 | [Molecular Weight]
333.86 | [MOL File]
119168-77-3.mol |
Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S36:Wear suitable protective clothing . | [RIDADR ]
2588 | [WGK Germany ]
3 | [RTECS ]
UQ6276400 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29331990 | [Hazardous Substances Data]
119168-77-3(Hazardous Substances Data) | [Toxicity]
LD50 in male, female rats (mg/kg): 595, 997 orally; >2000, >2000 dermally; LC50 in male rats (mg/m3): 2660 by inhalation (Inoue, Fukuchi) |
Hazard Information | Back Directory | [Chemical Properties]
Tan Solid | [Uses]
Acaricide. | [Uses]
Tebufenpyrad is a pyrazole acaricide and insecticide commonly used in commercial greenhouses. | [Definition]
ChEBI: Tebufenpyrad is a pyrazole acaricide and a pyrazole insecticide. It has a role as a mitochondrial NADH:ubiquinone reductase inhibitor. | [Metabolic pathway]
By incubation of tebufenpyrad with rat liver
homogenate, tebufenpyrad undergoes
biotransformation to yield the major metabolites N-(4-
tert-butylbenzyl)-4-chloro-3-(1-hydroxyethyl)-1-
methylpyrazole-5-carboxamide via hydroxylation of the
w-1-carbon of the ethyl group and N-[4-(1-carboxy-1-
methylethyl)benzyl]-4-chloro-3-ethyl-1-methylpyrazole-
5-carboxamide via oxidation of the methyl group in the
tert-butyl moiety to the carboxylic acid derivatives. When the rat is orally dosed tebufenpyrad, the major
metabolism pathway is via both hydroxylation and
oxidation reactions to yield N-[4-(1-carboxy-1-
methylethyl)benzyl]-4-chloro-3-(1-hydroxyethyl)-1-
methylpyrazole-5-carboxamide which is mainly
excreted in the urine. |
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