| Identification | More | [Name]
DNP | [CAS]
119-26-6 | [Synonyms]
1-(2,4-DINITROPHENYL)HYDRAZINE
2,4-DINITROPHENYLHYDRAZINE
DINITROPHENYL HYDRAZINE
DNP
DNPH
(2,4-dinitrophenyl)-hydrazin
1-Hydrazino-2,4-dinitrobenzene
2,4-Dinitrofenylhydrazin
2,4-dinitrophenyl-hydrazin
2,4-DNPH
Dnp-hydrazine
Hydrazine,(2,4-dinitrophenyl)-
2,4-DINITROPHENYLHYDRAZINE, MOIST. WITH WATER (H2O ~50%)
2,4-DINITROPHENYLHYDRAZINE HYDROCHLORIC ACID SOLTUION
2 4-DINITROPHENYLHYDRAZINE MOIST. WITH
2,4-DINITROPHENYLHYDRAZINE 99+% GR
2,4-DinitrophenylHydrazineForSynthesis
2,4-DinitrophenylHydrazineGr
2,4-Dinitrophenylhydrazine99%
2,4-Dinitrophenylhydrazine, moist with water | [EINECS(EC#)]
204-309-3 | [Molecular Formula]
C6H6N4O4 | [MDL Number]
MFCD00007578 | [Molecular Weight]
198.14 | [MOL File]
119-26-6.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
197-200 °C (lit.) | [Boiling point ]
335.43°C (rough estimate) | [density ]
0.843 g/mL at 20 °C
| [refractive index ]
n20/D 1.374
| [Fp ]
14 °C | [storage temp. ]
2-8°C
| [solubility ]
50% sulfuric acid: 10 mg/mL, clear, colorless
| [form ]
crystals | [pka]
12.1(at 25℃) | [color ]
Red | [PH Range]
Yellow (11.0) to brown (12.5) | [Stability:]
Stable when wet, but explosive when dry. May be shock sensitive when dry. Highly flammable. Incompatible with strong oxidizing agents. | [Water Solubility ]
slightly soluble | [Merck ]
14,3283 | [BRN ]
615586 | [Major Application]
Fuel cells, detecting microorganisms, antibacterial agent, treatment of acuteand chronic hepatitis, gynecopathy, cardiovascular diseases, cerebrovascular diseases | [InChIKey]
HORQAOAYAYGIBM-UHFFFAOYSA-N | [CAS DataBase Reference]
119-26-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Hydrazine, (2,4-dinitrophenyl)-(119-26-6) | [EPA Substance Registry System]
119-26-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn | [Risk Statements ]
R1:Explosive when dry.
R11:Highly Flammable.
R22:Harmful if swallowed.
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S35:This material and its container must be disposed of in a safe way .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 3380 4.1/PG 1
| [WGK Germany ]
3
| [RTECS ]
MV3325000
| [F ]
8 | [HazardClass ]
4.1 | [PackingGroup ]
II | [HS Code ]
29280000 |
| Questions And Answer(Q&A) | Back Directory | [Description]
2,4-Dinitrophenylhydrazine (abbreviated 2,4-DNP for short) is the chemical compound C6H3 (NO2) 2NHNH2, and it is often used to qualitatively test for carbonyl groups associated with aldehydes and ketones. The hydrazone derivatives can also be used as evidence toward the identity of the original compound. It is relatively sensitive to shock and friction; it is a shock explosive, so care must be taken with its use. To reduce its explosive hazard, it is usually supplied wet.
2,4-Dinitrophenylhydrazine is a compound with a benzene ring, two Nitro groups, and a hydrazine (two nitrogen atoms bonded directly to each other) functional group. It is used as a Brady's reagent to test the existing of a ketone or aldehyde. |
| Questions and Answers (Q&A) | Back Directory | [Uses]
2,4-Dinitrophenylhydrazine is known was Brady's reagent, a substituted hydrazine that is often used for qualitative testing of carbonyl groups associated with aldehydes and ketones.
|
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Definition]
ChEBI: A C-nitro compound that is phenylhydrazine substituted at the 2- and 4-positions by nitro groups. | [General Description]
2,4-Dinitrophenylhydrazine (DNPH), a hydrazine derivative, is a potential mutagenic agent. Its molecular and crystal structure has been analyzed. The intra- and intermolecular hydrogen bonds in DNPH have been investigated by vibrational spectroscopic analysis. The mechanism of isothermal degradation of DNPH has been studied by differential scanning calorimetry (DSC). | [Hazard]
2,4-Dinitrophenylhydrazine [119-26-6] is a flammable solid, which must be kept moist and is harmful if swallowed, inhaled, or absorbed through the skin. Concentrated sulfuric acid [7664-93-9] is poisonous and corrosive. Its mist can cause severe burns to all body tissue. It may be fatal if swallowed or by skin contact. It is harmful if inhaled and may cause cancer. Ethanol [64-17-5] is flammable and should be kept from ignition sources. Eye and face protection, protective clothing, and gloves must be worn. | [Purification Methods]
Crystallise DNPH from butan-1-ol, dioxane, EtOH, *C6H6 or EtOAc. The hydrochloride has m 186o (dec). [Beilstein 15 IV 380.] | [References]
1. SOME LIMITATIONS OF 2,4-DINITROPHENYLHYDRAZINE AS A REAGENT FOR CARBONYL GROUPS. DOI:10.1021/JO01226A003
2. Linstromberg, W. W.; Baumgarten, H. E. Organic Experiments, 6th ed.; Houghton Mifflin: Boston, 2002; p 175. Shriner, R. L.; Hermann, C. K. F.; Morrill, T. C.; Curtin, D. Y.; Fuson, R. C. The Systematic Identification of Organic Compounds, 8th ed.; Wiley; Hoboken, NJ, 2004; pp 278–279.
3. An Improved Preparation of 2,4-Dinitrophenylhydrazine Reagent. DOI:10.1021/ED082P1310.2 |
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