| Identification | More | [Name]
N-Acetyl-L-leucine | [CAS]
1188-21-2 | [Synonyms]
2-(ACETYLAMINO)-4-METHYLPENTANOIC ACID
AC-DL-LEU-OH
ACETYL-DL-LEUCINE
ACETYL-DL-LEUCINE, N-
ACETYL-L-LEUCINE
AC-LEUCINE
AC-LEU-OH
AKOS BBS-00004735
IFLAB-BB F0777-0821
N-ACETYL-DL-LEU
N-ACETYL-DL-LEUCINE
N-ACETYL LEUCINE
N-ACETYL-L-LEUCINE
N-ALPHA-ACETYL-DL-LEUCINE
N-ALPHA-ACETYL-L-LEUCINE
(S)-2-ACETYLAMINO-4-METHYL-PENTANOIC ACID
(S)-N-Acetylleucine
Leucine, N-acetyl-, L-
L-Leucine, N-acetyl-
N-Acetyl-L-lenucine | [EINECS(EC#)]
214-706-3 | [Molecular Formula]
C8H15NO3 | [MDL Number]
MFCD00026498 | [Molecular Weight]
173.21 | [MOL File]
1188-21-2.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
187-190 °C(lit.)
| [alpha ]
-24.5 º (c=4, MeOH) | [Boiling point ]
303.86°C (rough estimate) | [density ]
1.1599 (rough estimate) | [refractive index ]
-22 ° (C=5, EtOH) | [storage temp. ]
−20°C
| [solubility ]
DMSO (Slightly), Ethanol (Slightly), Water (Slightly, Heated) | [form ]
Crystalline Powder | [pka]
3.67±0.10(Predicted) | [color ]
White | [optical activity]
[α]25/D 23±3°, c = 2 in ethanol | [Water Solubility ]
0.81 g/100 mL (20 ºC) | [BRN ]
1724849 | [CAS DataBase Reference]
1188-21-2(CAS DataBase Reference) | [NIST Chemistry Reference]
L-leucine, n-acetyl-(1188-21-2) | [EPA Substance Registry System]
1188-21-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29241990 |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Uses]
N-Acetyl-L-(-)-leucine is used in the preparation of small molecule inhibitors of anti-apoptotic Bcl-2 family proteins. Also used in the preparation of amphiphilic copolymers involving hydrophobic amino acid and oligopeptide side chains for optical tumor imaging in vivo. | [Definition]
ChEBI: The N-acetyl derivative of L-leucine. |
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