| Identification | More | [Name]
2-Amino-2-methyl-1,3-propanediol | [CAS]
115-69-5 | [Synonyms]
2-AMINO-2-METHYL-1,3-PROPANEDIOL
AMMEDIOL
AMPD
LABOTEST-BB LT00233129
TIMTEC-BB SBB004360
1,1-Di(hydroxymethyl)ethylamine
1,3-Dihydroxy-2-methyl-2-propylamine
1,3-Propanediol, 2-amino-2-methyl-
2-amino-2-methyl-3-propanediol
2-Amino-2-methylpropan-1,3-diol
2-Amino-2-methylpropane-1,3-diol
2-Amino-2-methylpropanediol
3-Propanediol,2-amino-2-methyl-1
Aminoglycol
Aminomethyl propanediol
Gentimon
Isobutandiol-2-amine
pentaerythritoldichlorohydrin
2-Amino-2-methyl-1,3-propanediol
AMPD
2-AMINO-2-METHYL-1,3-PROPANEDIOLSIGMAULT RA | [EINECS(EC#)]
204-100-7 | [Molecular Formula]
C4H11NO2 | [MDL Number]
MFCD00004678 | [Molecular Weight]
105.14 | [MOL File]
115-69-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
100-110 °C (lit.) | [Boiling point ]
151 °C/10 mmHg (lit.) | [density ]
1.0509 (estimate) | [vapor density ]
3.63 (vs air)
| [vapor pressure ]
~10 mm Hg ( 152 °C)
| [refractive index ]
1.4754 (estimate) | [Fp ]
>100°C | [storage temp. ]
Store at RT. | [solubility ]
H2O: 1 M at 20 °C, clear, colorless
| [form ]
Crystalline Powder | [color ]
White | [PH]
10.0-12.0 (20℃, 0.5M in H2O) | [PH Range]
7.8 - 9.7 | [pka]
8.8(at 25℃) | [Stability:]
Stable. Combustible. May be moisture-sensitive. Incompatible with strong oxidizing agents, copper, aluminium, brass, strong acids. | [Water Solubility ]
2500 g/L (20 ºC) | [λmax]
λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.03 | [Merck ]
13,447 | [BRN ]
635708 | [LogP]
-1.31 at 22℃ | [CAS DataBase Reference]
115-69-5(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Amino-2-methyl-1,3-propanediol(115-69-5) | [EPA Substance Registry System]
115-69-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
UN 3259 8/PG 2
| [WGK Germany ]
1
| [RTECS ]
TY2975000
| [F ]
3-23 | [TSCA ]
Yes | [PackingGroup ]
III | [HS Code ]
29221980 | [Toxicity]
LD50 orally in Rabbit: 17000 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
white powder | [Uses]
A useful biological buffer2-Amino-2-methyl-1,3-propanediol is used to make surfactants, vulcanization accelerators and as a biological buffer. It acts as an absorbent for acidic gases and emulsifying agent for cosmetics, mineral oil, leather dressings, textile specialties and cleaning compounds. It is also used in hair sprays. It acts as a buffer for the determination of alkaline phosphatase activity and spacer in isotachophoresis of proteins. It serves as a reaction buffer for enzymes with an activity in the basic pH range such as alkaline phosphatase. Further, it is used in the preparation of 4-hydroxymethyl-4-methyl-oxazolidin-2-one. | [Uses]
Emulsifying agent (in soap form) for oils, fats, and waxes; absorbent for acidic gases; organic synthesis; cosmetics. | [Definition]
ChEBI: An aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2. | [Purification Methods]
Crystallise the diol three times from MeOH, dry in a stream of dry N2 at room temperature, then in a vacuum oven at 55o. Store it over CaCl2 [Hetzer & Bates J Phys Chem 66 308 1962]. [Beilstein 4 IV 1881.] |
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