| Identification | More | [Name]
Ethyl 4-piperidinecarboxylate | [CAS]
1126-09-6 | [Synonyms]
4-PIPERDINECARBOXYLIC ACID, ETHYL ESTER
4-PIPERIDINECARBOXYLIC ACID ETHYL ESTER
AKOS MSC-0737
ETHYL 4-PIPERIDINECARBOXYLATE
ETHYL ISONIPECOTATE
ETHYL PIPERIDINE-4-CARBOXYLATE
ISONIPECOTIC ACID ETHYL ESTER
ISONIPECOTINIC ACID ETHYL ESTER
LABOTEST-BB LT00159543
PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
RARECHEM AH CK 0180
TIMTEC-BB SBB004006
4-Carbethoxypiperidine
H-DL-Inp-OEt
Ethyl Isonipecotate(ethyl 4-Piperidinecarboxylate)
Hexahydroisonicotinic acid, ethyl ester
Ethyl isonipecotate, 98+%
Ethyl piperidine-4-carboxylate 97%
ethylpiperidine-2-carboxylate（hydrochloride
Ethyl 4-Piperidinecarboxylate (Ethyl isonipecotate) | [EINECS(EC#)]
214-416-7 | [Molecular Formula]
C8H15NO2 | [MDL Number]
MFCD00006003 | [Molecular Weight]
157.21 | [MOL File]
1126-09-6.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to slightly brown liquid | [Boiling point ]
204 °C(lit.)
| [density ]
1.02 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.459(lit.)
| [Fp ]
176 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [form ]
Liquid | [pka]
9.83±0.10(Predicted) | [color ]
Clear colorless to slightly brown | [Water Solubility ]
miscible | [Detection Methods]
HPLC,GC,NMR | [BRN ]
118419 | [CAS DataBase Reference]
1126-09-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethyl piperidine-4-carboxylate(1126-09-6) |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xi | [Risk Statements ]
R34:Causes burns.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN2735 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29333999 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to slightly brown liquid | [Uses]
Reactant for synthesis of SMN protein modulators and β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition. | [Uses]
Reactant for synthesis of:• ;SMN protein modulators1• ;β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition2• ;Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone3• ;RhoA inhibitors for cardiovascular disease therapy4• ;Saccharin derived Mannich bases as antimicrobials and antioxidants5Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates6 | [Synthesis Reference(s)]
Tetrahedron Letters, 23, p. 193, 1982 DOI: 10.1016/S0040-4039(00)86783-0 |
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