| Identification | More | [Name]
4-Methylpyridazine | [CAS]
1120-88-3 | [Synonyms]
4-METHYLPYRADIZINE
4-METHYLPYRIDAZINE
4-METHYLPYRIDAZINE 97% | [Molecular Formula]
C5H6N2 | [MDL Number]
MFCD00011594 | [Molecular Weight]
94.11 | [MOL File]
1120-88-3.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear yellow liquid | [Boiling point ]
98-100 °C/11 mmHg (lit.) | [density ]
1.06 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.521(lit.)
| [Fp ]
222 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Liquid | [pka]
3.74±0.10(Predicted) | [color ]
Clear yellow | [Specific Gravity]
1.060 | [λmax]
292nm(H2O)(lit.) | [BRN ]
105689 | [InChI]
InChI=1S/C5H6N2/c1-5-2-3-6-7-4-5/h2-4H,1H3 | [InChIKey]
AIKUBOPKWKZULG-UHFFFAOYSA-N | [SMILES]
C1=NN=CC=C1C | [CAS DataBase Reference]
1120-88-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear yellow liquid | [Uses]
4-Methylpyridazine was used in the preparation of series of novel pyridazine derivatives structurally related to bipyridine cardiotonics. | [Reactions]
4-methylpyridazine could be used as a starting material to synthesize a series of novel pyridazine derivatives structurally related to bipyridine cardiotonics[1].
Pyridazine (pydz) and 4-methylpyridazine (4Me-pydz) could form stable bis(monodentate) complexes of general formulae fac-[PtXMe3L2](X = Cl, Br or I) and fac-[ReX(CO)3L2](X = Cl, Br or I). These complexes in above-ambient temperature solutions exhibit 1,2-fluxional shifts between the nitrogen donor pairs of each ring[2]. | [General Description]
Products of reaction of methyl iodide with 4-methylpyridazine has been investigated by NMR spectra. Solvent free oxidation of 4-methylpyridazine by acetyl peroxyborate, peracetic acid and hydrogen peroxide has been reported. | [References]
[1] Haider N, et al. Pyridazine analogues of biologically active compounds. Part 5: Novel potential cardiotonics of the amrinone type. Organic Electronics, 1989.
[2] Abel E, et al. 1,2-Metallotropic shifts in trimethylplatinum(IV) and tricarbonylrhenium(I) halide complexes of pyridazine and 4-methylpyridazine. Journal of the Chemical Society, Dalton Transactions, 1994; 445-455. |
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