| Identification | Back Directory | [Name]
N-(2-pyridone-6-yl)-N',N'-di-n-propylformamidine | [CAS]
111757-17-6 | [Synonyms]
CGP 28014
N-(2-pyridone-6-yl)-N',N'-di-n-propylformamidine
Methanimidamide, N'-(1,6-dihydro-6-oxo-2-pyridinyl)-N,N-dipropyl- | [Molecular Formula]
C12H19N3O | [MDL Number]
MFCD01715197 | [MOL File]
111757-17-6.mol | [Molecular Weight]
221.3 |
| Hazard Information | Back Directory | [Description]
CGP-28014 is a catechol-O-methyltransferase inhibitor potentially for the treatment of Parkinson's disease.Although CGP-28014 increases the renal excretion of both dopamine and dihydroxyphenylacetic acid (DOPAC) it does not affect renal sodium handling indicating a different mechanism of action. CGP-28014 significantly reduced the levels of homovanillic acid (HVA), but did not modify DA and 3,4-dihydroxyphenylacetic acid (DOPAC). | [Definition]
ChEBI: CGP 28014 is a pyridone. |
|
|