| Identification | More | [Name]
2-Amino-5-chloropyridine | [CAS]
1072-98-6 | [Synonyms]
2-AMINO-5-CHLOROPYRIDINE
5-CHLORO-2-AMINOPYRIDINE
5-CHLORO-2-PYRIDINAMINE
5-CHLORO-2-PYRIDYLAMINE
5-CHLORO-A-PYRIDYLAMINE
5-CHLOROPYRIDIN-2-AMINE
5-CHLOROPYRIDIN-2-YLAMINE
AKOS 91155
AMINO(2-)-5-CHLOROPYRIDINE
TIMTEC-BB SBB000059
2-Pyridinamine, 5-chloro-
Pyridine, 2-amino-5-chloro-
2-Amino-5-Chloro Pyriine
2-AMINO-5-CHLOROPYRIDINE 99%
2-AMINO-5-CHLIROPYRIDINE
2-Pyridinamine,5-chloro-(9CI)
2-Amino-5-chloropyridine
2-Amino-5-chloropyridine
2-AMINO-5-CHLOROPYRIDINE 5-CHLORO-PYRIDIN-2-YLAMINE
5-Chloro-2-pyridineamine | [EINECS(EC#)]
214-020-4 | [Molecular Formula]
C5H5ClN2 | [MDL Number]
MFCD00006324 | [Molecular Weight]
128.56 | [MOL File]
1072-98-6.mol |
| Chemical Properties | Back Directory | [Appearance]
beige to beige-brown crystalline powder | [Melting point ]
135-138 °C (lit.) | [Boiling point ]
127-128 °C/11 mmHg (lit.) | [density ]
1.2417 (rough estimate) | [refractive index ]
1.5110 (estimate) | [Fp ]
160 °C
| [storage temp. ]
2-8°C | [solubility ]
1.0g/l | [form ]
Crystalline Powder | [pka]
4.67±0.13(Predicted) | [color ]
Beige to beige-brown | [Water Solubility ]
1 g/L (20 ºC) | [Detection Methods]
HPLC,NMR | [BRN ]
108735 | [InChIKey]
MAXBVGJEFDMHNV-UHFFFAOYSA-N | [CAS DataBase Reference]
1072-98-6(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Amino-5-chloropyridine(1072-98-6) | [EPA Substance Registry System]
1072-98-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Harmful | [HazardClass ]
IRRITANT | [HS Code ]
29333999 |
| Hazard Information | Back Directory | [Chemical Properties]
beige to beige-brown crystalline powder | [Uses]
5-Chloro-2-pyridinamine is a useful synthetic intermediate. It can be used to synthesize zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 41, p. 93, 1976 DOI: 10.1021/jo00863a020 | [Purification Methods]
Recrystallise this base from pet ether. It sublimes at 50o/0.5mm. [Beilstein 22 II 332, 22/8 V 541.] |
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