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ChemicalBook--->CAS DataBase List--->105650-23-5

105650-23-5

105650-23-5 Structure

105650-23-5 Structure
IdentificationMore
[Name]

2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
[CAS]

105650-23-5
[Synonyms]

2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
PHIP
5-b)pyridin-2-amine,1-methyl-6-phenyl-1h-imidazo(
5-b)pyridine,2-amino-1-methyl-6-phenyl-1h-imidazo(
5-b)pyridine,2-amino-1-methyl-6-phenyl-imidazo(
Amino-1-methyl-6-phenylimidazo[4.5-b]pyridine
1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine
2-AMINO-1-METHYL-6-PHENYLIMADAZO(4,5-B)PYRIDINE
2-AMINO-1-METHYL-6-PHENYL-1H-IMIDAZO[4,5-B]PYRIDINE
2-AMINO-1-METHYL-6-PHENOLIMIDAZO[4,5-B]PYRIDINE
2-Amino-1-methyl-6-phenylimidazo[4,5,b]pyridine, (PhIP)
1-Methyl-6-phenyl-1H-imidazo[4,5-β]pyridin-2-amine
2-Amino-1-methyl-6-phenylimidazo[4,5-β]pyridine
[Molecular Formula]

C13H12N4
[MDL Number]

MFCD00210745
[Molecular Weight]

224.26
[MOL File]

105650-23-5.mol
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

300
[Boiling point ]

355.66°C (rough estimate)
[density ]

1.2067 (rough estimate)
[refractive index ]

1.5890 (estimate)
[storage temp. ]

Refrigerator
[solubility ]

DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
[form ]

A crystalline solid
[pka]

7.72±0.30(Predicted)
[color ]

White to light yellow
[biological source]

synthetic
[Usage]

Carcinogen
[CAS DataBase Reference]

105650-23-5(CAS DataBase Reference)
[IARC]

2B (Vol. 56) 1993
Safety DataBack Directory
[Hazard Codes ]

T
[Hazard Note ]

Toxic
[HS Code ]

29332900
[Safety Profile]

Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx,.
[Hazardous Substances Data]

105650-23-5(Hazardous Substances Data)
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

Carcinogen
[Definition]

ChEBI: An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in coo ed meat and fish.
[Biological Activity]

Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.
[Carcinogenicity]

PhIP is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting genotoxicity data.
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