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ChemicalBook--->CAS DataBase List--->102036-29-3

102036-29-3

102036-29-3 Structure

102036-29-3 Structure
IdentificationBack Directory
[Name]

(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
[CAS]

102036-29-3
[Synonyms]

Q-100961
FT-0689654
Protosappanin B
(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
(7S,12aS)-7,8-Dihydro-7-(hydroxymethyl)-6H-dibenz[b,d]oxocin-3,7,10,11-tetrol
6H-Dibenz[b,d]oxocin-3,7,10,11-tetrol,7,8-dihydro-7-(hydroxymethyl)-, (7S,12aS)-
[Molecular Formula]

C16H16O6
[MDL Number]

MFCD29048516
[MOL File]

102036-29-3.mol
[Molecular Weight]

304.29
Chemical PropertiesBack Directory
[Boiling point ]

655.5±55.0 °C(Predicted)
[density ]

1.507
[storage temp. ]

Sealed in dry,2-8°C
[form ]

Solid
[pka]

9.20±0.40(Predicted)
[color ]

Light yellow to orange
Hazard InformationBack Directory
[Description]

Research results in recent years have shown that sumac extract has a significant inhibitory effect on a variety of tumor cells. Protosappanin B is one of the main components in hematoxylin. It has inhibitory effect on the proliferation of both BTT and T24 cells, and as Protosappanin B acts on each cell for a longer period of time, its killing effect is gradually enhanced, showing a time-dependence.
[Chemical Properties]

Soluble in methanol, DMSO, insoluble in petroleum ether and other solvents.
[Biological Activity]

Protosappanin B is a polyphenol extracted from hematoxylin and has anti-tumor effects. In human bladder cancer cells, it can arrest the G1 phase of the cell cycle and induce apoptosis.
[target]

Apoptosis

[storage]

4°C, protect from light
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