Identification | Back Directory | [Name]
CY 208-243 | [CAS]
100999-26-6 | [Synonyms]
CY 208-243 (6aR)-4,6,6aα,7,8,12bβ-Hexahydro-7-methylindolo[4,3-ab]phenanthridine (6aR,12bβ)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-ab]phenanthridine (6aα,12bβ)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-ab]phenanthridine (-)-(6AR,12BR)-4,6,6A,7,8,12B-HEXAHYDRO-7-METHYLINDOLO[4,3-A]PHENANTHRIDIN (-)-(6aR,12bR)-4,6,6a,7,8,12β-Hexahydro-7-methylindolo[4,3-a]phenanthridin [6aR,12bR,(-)]-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-ab]phenanthridine Indolo[4,3-ab]phenanthridine, 4,6,6a,7,8,12b-hexahydro-7-methyl-, (6aR,12bR)- | [Molecular Formula]
C19H18N2 | [MDL Number]
MFCD06407823 | [MOL File]
100999-26-6.mol | [Molecular Weight]
274.36 |
Chemical Properties | Back Directory | [Boiling point ]
466.5±33.0 °C(Predicted) | [density ]
1.225±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Soluble to 100 mM in DMSO | [form ]
Powder | [pka]
17.40±0.20(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
CY 208-243 is a selective D1DR receptor agonist. | [Definition]
ChEBI:LSM-3788 is a member of phenanthridines. | [Biological Activity]
Centrally active dopamine D 1 receptor agonist, selective over D 2 receptor sites. Stimulates adenylate cyclase in rat striatal homogenates with an EC 50 of 125 nM. Unlike SKF 38393 ((?-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide ), it exerts anti-Parkinsonian activity in animal models. | [storage]
Store at RT |
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