Z-VAL-ILE-OH synthesis
- Product Name:Z-VAL-ILE-OH
- CAS Number:41486-97-9
- Molecular formula:C19H28N2O5
- Molecular Weight:364.44
73-32-5
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![N-[(Phenylmethoxy)carbonyl]-L-valine 1H-benzotriazol-1-yl ester](/CAS/20210305/GIF/126814-51-5.gif)
126814-51-5
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41486-97-9
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$75.00/100mg
Yield:41486-97-9 95%
Reaction Conditions:
Stage #1: N-(Benzyloxycarbonyl)-L-valine 1H-benzotriazol-1-yl esterwith 4-methyl-morpholine;benzotriazol-1-ol;O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate in N,N-dimethyl-formamide at 20; for 0.333333 h;Substitution;
Stage #2: L-isoleucinewith barium(II) iodide;triethylamine in N,N-dimethyl-formamide at 20; for 1 h;Condensation;
References:
Raydnov, M. G.;Klimenko, L. V.;Mitin, Yu. V. [Russian Journal of Bioorganic Chemistry,1999,vol. 25,# 5,p. 283 - 287][Bioorganicheskaya Khimiya,1999,vol. 25,# 5,p. 323 - 328]